Literature DB >> 9145892

Comparative activities of amikacin against Mycobacterium avium complex in nude and beige mice.

N Lounis1, B Ji, C Truffot-Pernot, J Grosset.   

Abstract

After 4 weeks of treatment, clarithromycin (CLAR) and amikacin showed similar antimicrobial activities against the Mycobacterium avium complex in mice. There was a difference, however, in the effectiveness of the drugs in different types of mice: both drugs displayed bactericidal effects in beige mice but only bacteriostatic effects in nude mice. Because the effectiveness of CLAR is less in nude mice than in beige mice, the predictive value of the nude mouse model for the efficacy of chemotherapy is less than that of the beige mouse model.

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Year:  1997        PMID： 9145892      PMCID： PMC163873     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Amikacin, ciprofloxacin, and imipenem treatment for disseminated Mycobacterium avium complex infection of beige mice.

Authors:  C B Inderlied; P T Kolonoski; M Wu; L S Young
Journal:  Antimicrob Agents Chemother       Date:  1989-02       Impact factor: 5.191

2.  In vivo activity of amikacin alone or in combination with clofazimine or rifabutin or both against acute experimental Mycobacterium avium complex infections in beige mice.

Authors:  P R Gangadharam; V K Perumal; N R Podapati; L Kesavalu; M D Iseman
Journal:  Antimicrob Agents Chemother       Date:  1988-09       Impact factor: 5.191

3.  Liposome-encapsulated-amikacin therapy of Mycobacterium avium complex infection in beige mice.

Authors:  M H Cynamon; C E Swenson; G S Palmer; R S Ginsberg
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

4.  Effectiveness of various antimicrobial agents against Mycobacterium avium complex in the beige mouse model.

Authors:  B Ji; N Lounis; C Truffot-Pernot; J Grosset
Journal:  Antimicrob Agents Chemother       Date:  1994-11       Impact factor: 5.191

5.  The beige mutation in the mouse. I. A stem cell predetermined impairment in natural killer cell function.

Authors:  J C Roder
Journal:  J Immunol       Date:  1979-11       Impact factor: 5.422

6.  Clarithromycin therapy for bacteremic Mycobacterium avium complex disease. A randomized, double-blind, dose-ranging study in patients with AIDS. AIDS Clinical Trials Group Protocol 157 Study Team.

Authors:  R E Chaisson; C A Benson; M P Dube; L B Heifets; J A Korvick; S Elkin; T Smith; J C Craft; F R Sattler
Journal:  Ann Intern Med       Date:  1994-12-15       Impact factor: 25.391

7.  Surveillance of AIDS-defining conditions in the United States. Adult/Adolescent Spectrum of HIV Disease Project Group.

Authors:  J L Jones; D L Hanson; S Y Chu; P L Fleming; D J Hu; J W Ward
Journal:  AIDS       Date:  1994-10       Impact factor: 4.177

8.  Mycobacterium avium-complex infections in normal and immunodeficient mice.

Authors:  F M Collins; R W Stokes
Journal:  Tubercle       Date:  1987-06

9.  Clarithromycin and other antimicrobial agents in the treatment of disseminated Mycobacterium avium infections in patients with acquired immunodeficiency syndrome.

Authors:  B Dautzenberg; T Saint Marc; M C Meyohas; M Eliaszewitch; F Haniez; A M Rogues; S De Wit; L Cotte; J P Chauvin; J Grosset
Journal:  Arch Intern Med       Date:  1993-02-08

10.  Selection of clarithromycin-resistant Mycobacterium avium complex during combined therapy using the beige mouse model.

Authors:  N Lounis; B Ji; C Truffot-Pernot; J Grosset
Journal:  Antimicrob Agents Chemother       Date:  1995-03       Impact factor: 5.191
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  3 in total

1.  Characterization of mouse models of Mycobacterium avium complex infection and evaluation of drug combinations.

Authors:  Claire Andréjak; Deepak V Almeida; Sandeep Tyagi; Paul J Converse; Nicole C Ammerman; Jacques H Grosset
Journal:  Antimicrob Agents Chemother       Date:  2015-01-26       Impact factor: 5.191

2.  Mouse model for efficacy testing of antituberculosis agents via intrapulmonary delivery.

Authors:  Mercedes Gonzalez-Juarrero; Lisa K Woolhiser; Elizabeth Brooks; Mary Ann DeGroote; Anne J Lenaerts
Journal:  Antimicrob Agents Chemother       Date:  2012-04-30       Impact factor: 5.191

3.  Novel Screening System of Virulent Strains for the Establishment of a Mycobacterium avium Complex Lung Disease Mouse Model Using Whole-Genome Sequencing.

Authors:  Koji Furuuchi; Shintaro Seto; Hajime Nakamura; Haruka Hikichi; Akiko Miyabayashi; Keiko Wakabayashi; Kazue Mizuno; Teruaki Oka; Kozo Morimoto; Minako Hijikata; Naoto Keicho
Journal:  Microbiol Spectr       Date:  2022-05-17
  3 in total

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