OBJECTIVE: This study examined glucose metabolism in the anterior and posterior cingulate cortex in schizophrenia. METHOD: Fifty unmedicated male schizophrenic patients and 24 normal men were studied with positron emission tomography. RESULTS: Compared with the normal men, the schizophrenic patients had lower relative metabolic rates in the anterior cingulate and higher rates in the posterior cingulate. CONCLUSIONS: The findings suggest hypofunction in the anterior cingulate cortex in schizophrenia.
OBJECTIVE: This study examined glucose metabolism in the anterior and posterior cingulate cortex in schizophrenia. METHOD: Fifty unmedicated male schizophrenicpatients and 24 normal men were studied with positron emission tomography. RESULTS: Compared with the normal men, the schizophrenicpatients had lower relative metabolic rates in the anterior cingulate and higher rates in the posterior cingulate. CONCLUSIONS: The findings suggest hypofunction in the anterior cingulate cortex in schizophrenia.
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Authors: Rick P F Wolthusen; Garth Coombs; Emily A Boeke; Stefan Ehrlich; Stephanie N DeCross; Shahin Nasr; Daphne J Holt Journal: Biol Psychiatry Cogn Neurosci Neuroimaging Date: 2017-07-13
Authors: Daphne J Holt; Balaji Lakshmanan; Oliver Freudenreich; Donald C Goff; Scott L Rauch; Gina R Kuperberg Journal: Schizophr Bull Date: 2009-07-15 Impact factor: 9.306