| Literature DB >> 9134749 |
D A Venables1, G P Concepción, S S Matsumoto, L R Barrows, C M Ireland.
Abstract
Makaluvamine N (1), a new pyrroloiminoquinone, was isolated from the Philippine sponge Zyzzya fuliginosa, together with the known compounds makaluvamines A, C, D, E (2-5), and I (6). The structure of 1 was determined by spectroscopic investigation. Makaluvamine N demonstrated an ability to inhibit the catalytic activity of topoisomerase II.Entities:
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Year: 1997 PMID: 9134749 DOI: 10.1021/np9607262
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050