Literature DB >> 9131149

Ether lipid metabolism, GPI anchor biosynthesis, and signal transduction are putative targets for anti-leishmanial alkyl phospholipid analogues.

H Lux1, D T Hart, P J Parker, T Klenner.   

Abstract

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Year:  1996        PMID： 9131149     DOI： 10.1007/978-1-4899-0179-8_33

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


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  13 in total

1.  Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.

Authors:  Victor B Saraiva; Daniel Gibaldi; José O Previato; Lucia Mendonça-Previato; Marcelo T Bozza; Célio G Freire-De-Lima; Norton Heise
Journal:  Antimicrob Agents Chemother       Date:  2002-11       Impact factor: 5.191

2.  In vitro and in vivo interactions between miltefosine and other antileishmanial drugs.

Authors:  Karin Seifert; Simon L Croft
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

3.  Hexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis.

Authors:  Fred Widmer; Lesley C Wright; Daniel Obando; Rosemary Handke; Ranjini Ganendren; David H Ellis; Tania C Sorrell
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

4.  Effects of miltefosine and other alkylphosphocholines on human intestinal parasite Entamoeba histolytica.

Authors:  K Seifert; M Duchêne; W H Wernsdorfer; H Kollaritsch; O Scheiner; G Wiedermann; T Hottkowitz; H Eibl
Journal:  Antimicrob Agents Chemother       Date:  2001-05       Impact factor: 5.191

5.  Miltefosine efficiently eliminates Leishmania major amastigotes from infected murine dendritic cells without altering their immune functions.

Authors:  Klaus Griewank; Caroline Gazeau; Andreas Eichhorn; Esther von Stebut
Journal:  Antimicrob Agents Chemother       Date:  2009-12-07       Impact factor: 5.191

6.  Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator.

Authors:  J M Pérez-Victoria; F J Pérez-Victoria; A Parodi-Talice; I A Jiménez; A G Ravelo; S Castanys; F Gamarro
Journal:  Antimicrob Agents Chemother       Date:  2001-09       Impact factor: 5.191

7.  Miltefosine (Impavido): the first oral treatment against leishmaniasis.

Authors:  H Sindermann; S L Croft; K R Engel; W Bommer; H J Eibl; C Unger; J Engel
Journal:  Med Microbiol Immunol       Date:  2003-09-26       Impact factor: 3.402

8.  Possible mechanism of miltefosine-mediated death of Leishmania donovani.

Authors:  Navin K Verma; Chinmoy S Dey
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

9.  Miltefosine induces apoptosis-like death in Leishmania donovani promastigotes.

Authors:  Caroline Paris; Philippe M Loiseau; Christian Bories; Jaqueline Bréard
Journal:  Antimicrob Agents Chemother       Date:  2004-03       Impact factor: 5.191

10.  Structures, targets and recent approaches in anti-leishmanial drug discovery and development.

Authors:  Karin Seifert
Journal:  Open Med Chem J       Date:  2011-03-09
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