Literature DB >> 912986

Low doses of 1,25-dihydroxycholecalciferol increase mature bone mass in adult normal rats.

S E Larsson, R Lorentzon, L Boquist.   

Abstract

Low doses of 1,25-DHCC cause a significant increase in trabecular and cortical bone mass of the mature rat skeleton by stimulated endosteal bone formation. The increased serum contents of calcium and inorganic phosphate give rise to a moderate nephrocalcinosis. An increased bone resorption occurs upon toxic dose levels causing profound nephrocalcinosis. Similar doses of 25-HCC do not affect the mature bone.

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Year:  1977        PMID： 912986

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN： 0009-921X            Impact factor:   4.176


  12 in total

1.  Cell density-dependent vitamin D effects on calcium accumulation in rat osteogenic sarcoma cells (ROS 17/2).

Authors:  Y S Kim; S J Birge; L V Avioli; R Miller
Journal:  Calcif Tissue Int       Date:  1987-10       Impact factor: 4.333

2.  Stimulation of undermineralized matrix formation by 1,25 dihydroxyvitamin D3 in long bones of rats.

Authors:  J M Hock; M Gunness-Hey; J Poser; H Olson; N H Bell; L G Raisz
Journal:  Calcif Tissue Int       Date:  1986-02       Impact factor: 4.333

3.  Histomorphometric evaluation of the effects of intermittent 1,25-dihydroxycholecalciferol administration on cortical bone remodeling in adult dogs.

Authors:  W B High; C C Capen; H E Black
Journal:  Am J Pathol       Date:  1981-07       Impact factor: 4.307

4.  Acute effects of Solanum malacoxylon on bone formation rates in growing rats.

Authors:  R W Norrdin; C S de Barros; M L Queille; M Carré; L Miravet
Journal:  Calcif Tissue Int       Date:  1979-11-06       Impact factor: 4.333

5.  The influence of dihydroxylated vitamin D metabolites on bone formation in the chick.

Authors:  I R Dickson; A K Hall; S S Jande
Journal:  Calcif Tissue Int       Date:  1984-01       Impact factor: 4.333

6.  Effect of 1 alpha-vitamin D3 on bone strength and composition in growing rats with and without corticosteroid treatment.

Authors:  J Aerssens; R Van Audekercke; M Talalaj; P Van Vlasselaer; E Bramm; P Geusens; J Dequeker
Journal:  Calcif Tissue Int       Date:  1994-12       Impact factor: 4.333

7.  Effects of 1,25-dihydroxycholecalciferol on fracture healing. Calcium, phosphate, and zinc in callus and serum.

Authors:  O Andreen; S E Larsson
Journal:  Arch Orthop Trauma Surg       Date:  1984

8.  Light- and electron-microscopic evaluation of the effects of 1,25-dihydroxyvitamin D3 on bone of thyroparathyroidectomized rats.

Authors:  S E Weisbrode; C C Capen; A W Norman
Journal:  Am J Pathol       Date:  1979-11       Impact factor: 4.307

9.  1,25 dihydroxyvitamin D3 alone or in combination with parathyroid hormone does not increase bone mass in young rats.

Authors:  M Gunness-Hey; I Gera; J Fonseca; L G Raisz; J M Hock
Journal:  Calcif Tissue Int       Date:  1988-11       Impact factor: 4.333

10.  Serum calcium and phosphate concentrations and parathyroid morphology in rats treated with vitamin D metabolites.

Authors:  L Boquist; S E Larsson; R Lorentzon
Journal:  Urol Res       Date:  1980
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