Literature DB >> 9125150

Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer.

T Kishi1, H Sasaki, N Akiyama, T Ishizuka, H Sakamoto, S Aizawa, T Sugimura, M Terada.   

Abstract

Many amplified-chromosome regions in human cancers have been identified, while there are only a limited number of reports for amplified genes in a single amplicon. We recently isolated four cDNA clones, A39, B47, C51, and CAB1, from 500 kilobases of yeast artificial chromosome DNA containing the c-ERBB-2 gene. B47 consisted of 615 base pairs and had about 85% homology with the corresponding sequence of mouse Grb-7. We report here the structure of human GRB-7 cDNA, and we report that the amounts of mRNA for c-ERBB-2, CAB1, and GRB-7 were elevated in concordance with the amplification.

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Year:  1997        PMID： 9125150     DOI： 10.1006/bbrc.1997.6218

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  10 in total

1.  Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide.

Authors:  Min Y Yap; Matthew C J Wilce; Daniel J Clayton; Patrick Perlmutter; Marie-Isabel Aguilar; Jacqueline A Wilce
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-11-26

2.  Preparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist.

Authors:  Nigus D Ambaye; Menachem J Gunzburg; Daouda A K Traore; Mark P Del Borgo; Patrick Perlmutter; Matthew C J Wilce; Jacqueline A Wilce
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2014-01-21       Impact factor: 1.056

3.  Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor.

Authors:  K Thömmes; J Lennartsson; M Carlberg; L Rönnstrand
Journal:  Biochem J       Date:  1999-07-01       Impact factor: 3.857

4.  Grb7 gene amplification and protein expression by FISH and IHC in ovarian cancer.

Authors:  Manman Zeng; Zhu Yang; Xiaoyu Hu; Yi Liu; Xiaotao Yang; Hailong Ran; Yanan Li; Xu Li; Qiubo Yu
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

5.  Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis.

Authors:  Pei-Yu Chu; Ling-Ya Huang; Chun-Hua Hsu; Chun-Chi Liang; Jun-Lin Guan; Ting-Hsuan Hung; Tang-Long Shen
Journal:  J Biol Chem       Date:  2009-05-27       Impact factor: 5.157

6.  Identification of the CAB2/hCOS16 gene required for the repair of DNA double-strand breaks on a core amplified region of the 17q12 locus in breast and gastric cancers.

Authors:  Masahiko Nezu; Michiko Nishigaki; Tomoki Ishizuka; Yoshitaka Kuwahara; Chikako Tanabe; Kazuhiko Aoyagi; Hiromi Sakamoto; Yasushi Saito; Teruhiko Yoshida; Hiroki Sasaki; Masaaki Terada
Journal:  Jpn J Cancer Res       Date:  2002-11

7.  Genomic organization and control of the grb7 gene family.

Authors:  E Lucas-Fernández; I García-Palmero; A Villalobo
Journal:  Curr Genomics       Date:  2008-03       Impact factor: 2.236

8.  Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.

Authors:  Corrine J Porter; Jacqueline M Matthews; Joel P Mackay; Sharon E Pursglove; Jason W Schmidberger; Peter J Leedman; Stephanie C Pero; David N Krag; Matthew C J Wilce; Jacqueline A Wilce
Journal:  BMC Struct Biol       Date:  2007-09-25

9.  Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells.

Authors:  S C Pero; G S Shukla; M M Cookson; S Flemer; D N Krag
Journal:  Br J Cancer       Date:  2007-04-10       Impact factor: 7.640

10.  Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.

Authors:  Menachem J Gunzburg; Ketav Kulkarni; Gabrielle M Watson; Nigus D Ambaye; Mark P Del Borgo; Rebecca Brandt; Stephanie C Pero; Patrick Perlmutter; Matthew C J Wilce; Jacqueline A Wilce
Journal:  Sci Rep       Date:  2016-06-03       Impact factor: 4.379
  10 in total

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