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Literature DB >> 9122152

The Alzheimer family of diseases: many etiologies, one pathogenesis?

J Hardy¹.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 1997 PMID： 9122152 PMCID： PMC33655 DOI： 10.1073/pnas.94.6.2095

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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20 in total

Review 1. Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease.

Authors: D J Selkoe
Journal: Annu Rev Cell Biol Date: 1994

2. The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue.

Authors: T Tomita; K Maruyama; T C Saido; H Kume; K Shinozaki; S Tokuhiro; A Capell; J Walter; J Grünberg; C Haass; T Iwatsubo; K Obata
Journal: Proc Natl Acad Sci U S A Date: 1997-03-04 Impact factor: 11.205

3. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.

Authors: A Goate; M C Chartier-Harlin; M Mullan; J Brown; F Crawford; L Fidani; L Giuffra; A Haynes; N Irving; L James
Journal: Nature Date: 1991-02-21 Impact factor: 49.962

4. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease.

Authors: J T Jarrett; E P Berger; P T Lansbury
Journal: Biochemistry Date: 1993-05-11 Impact factor: 3.162

Review 5. Amyloid deposition as the central event in the aetiology of Alzheimer's disease.

Authors: J Hardy; D Allsop
Journal: Trends Pharmacol Sci Date: 1991-10 Impact factor: 14.819

6. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.

Authors: D Games; D Adams; R Alessandrini; R Barbour; P Berthelette; C Blackwell; T Carr; J Clemens; T Donaldson; F Gillespie
Journal: Nature Date: 1995-02-09 Impact factor: 49.962

7. Candidate gene for the chromosome 1 familial Alzheimer's disease locus.

Authors: E Levy-Lahad; W Wasco; P Poorkaj; D M Romano; J Oshima; W H Pettingell; C E Yu; P D Jondro; S D Schmidt; K Wang
Journal: Science Date: 1995-08-18 Impact factor: 47.728

8. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene.

Authors: D Levitan; I Greenwald
Journal: Nature Date: 1995-09-28 Impact factor: 49.962

9. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

Authors: R Sherrington; E I Rogaev; Y Liang; E A Rogaeva; G Levesque; M Ikeda; H Chi; C Lin; G Li; K Holman; T Tsuda; L Mar; J F Foncin; A C Bruni; M P Montesi; S Sorbi; I Rainero; L Pinessi; L Nee; I Chumakov; D Pollen; A Brookes; P Sanseau; R J Polinsky; W Wasco; H A Da Silva; J L Haines; M A Perkicak-Vance; R E Tanzi; A D Roses; P E Fraser; J M Rommens; P H St George-Hyslop
Journal: Nature Date: 1995-06-29 Impact factor: 49.962

10. Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions.

Authors: S W L'Hernault; P M Arduengo
Journal: J Cell Biol Date: 1992-10 Impact factor: 10.539

36 in total

1. In search of gamma-secretase: presenilin at the cutting edge.

Authors: D J Selkoe; M S Wolfe
Journal: Proc Natl Acad Sci U S A Date: 2000-05-23 Impact factor: 11.205

2. Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering.

Authors: Winnie Yong; Aleksey Lomakin; Marina D Kirkitadze; David B Teplow; Sow-Hsin Chen; George B Benedek
Journal: Proc Natl Acad Sci U S A Date: 2001-12-26 Impact factor: 11.205

3. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.

Authors: William P Esler; W Taylor Kimberly; Beth L Ostaszewski; Wenjuan Ye; Thekla S Diehl; Dennis J Selkoe; Michael S Wolfe
Journal: Proc Natl Acad Sci U S A Date: 2002-02-26 Impact factor: 11.205

4. Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice.

Authors: Götz Heilbronner; Yvonne S Eisele; Franziska Langer; Stephan A Kaeser; Renata Novotny; Amudha Nagarathinam; Andreas Aslund; Per Hammarström; K Peter R Nilsson; Mathias Jucker
Journal: EMBO Rep Date: 2013-09-03 Impact factor: 8.807

5. C terminus of presenilin is required for overproduction of amyloidogenic Abeta42 through stabilization and endoproteolysis of presenilin.

Authors: T Tomita; R Takikawa; A Koyama; Y Morohashi; N Takasugi; T C Saido; K Maruyama; T Iwatsubo
Journal: J Neurosci Date: 1999-12-15 Impact factor: 6.167

10. The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity.

Authors: Asad Jan; Ozgun Gokce; Ruth Luthi-Carter; Hilal A Lashuel
Journal: J Biol Chem Date: 2008-08-11 Impact factor: 5.157