Literature DB >> 10823929

In search of gamma-secretase: presenilin at the cutting edge.

D J Selkoe1, M S Wolfe.   

Abstract

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Year:  2000        PMID： 10823929      PMCID： PMC33989          DOI： 10.1073/pnas.97.11.5690

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  34 in total

Review 1.  HIV protease: a novel chemotherapeutic target for AIDS.

Authors:  J R Huff
Journal:  J Med Chem       Date:  1991-08       Impact factor: 7.446

2.  Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state.

Authors:  Y M Li; M T Lai; M Xu; Q Huang; J DiMuzio-Mower; M K Sardana; X P Shi; K C Yin; J A Shafer; S J Gardell
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

3.  Kinetics of the inhibition of human renin by an inhibitor containing a hydroxyethylene dipeptide isostere.

Authors:  W M Kati; D T Pals; S Thaisrivongs
Journal:  Biochemistry       Date:  1987-12-01       Impact factor: 3.162

4.  Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein.

Authors:  X Lin; G Koelsch; S Wu; D Downs; A Dashti; J Tang
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-15       Impact factor: 11.205

5.  A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.

Authors:  C Brou; F Logeat; N Gupta; C Bessia; O LeBail; J R Doedens; A Cumano; P Roux; R A Black; A Israël
Journal:  Mol Cell       Date:  2000-02       Impact factor: 17.970

6.  A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1.

Authors:  J S Mumm; E H Schroeter; M T Saxena; A Griesemer; X Tian; D J Pan; W J Ray; R Kopan
Journal:  Mol Cell       Date:  2000-02       Impact factor: 17.970

7.  Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.

Authors:  U Leimer; K Lun; H Romig; J Walter; J Grünberg; M Brand; C Haass
Journal:  Biochemistry       Date:  1999-10-12       Impact factor: 3.162

8.  Amyloid beta-peptide is produced by cultured cells during normal metabolism.

Authors:  C Haass; M G Schlossmacher; A Y Hung; C Vigo-Pelfrey; A Mellon; B L Ostaszewski; I Lieberburg; E H Koo; D Schenk; D B Teplow
Journal:  Nature       Date:  1992-09-24       Impact factor: 49.962

9.  Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids.

Authors:  P Seubert; C Vigo-Pelfrey; F Esch; M Lee; H Dovey; D Davis; S Sinha; M Schlossmacher; J Whaley; C Swindlehurst
Journal:  Nature       Date:  1992-09-24       Impact factor: 49.962

10.  Production of the Alzheimer amyloid beta protein by normal proteolytic processing.

Authors:  M Shoji; T E Golde; J Ghiso; T T Cheung; S Estus; L M Shaffer; X D Cai; D M McKay; R Tintner; B Frangione
Journal:  Science       Date:  1992-10-02       Impact factor: 47.728
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  14 in total

1.  Gamma -secretase inhibitors repress thymocyte development.

Authors:  B K Hadland; N R Manley; D Su ; G D Longmore; C L Moore; M S Wolfe; E H Schroeter; R Kopan
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-19       Impact factor: 11.205

2.  Changes in presenilin 2-binding Wnt proteins, behavior, amyloid-beta 42, gamma-secretase activity, and testosterone sensitivity in transgenic mice coexpressing tetracycline-controlled transactivator and human mutant presenilin 2.

Authors:  Dae Y Hwang; Jung S Cho; Chuel K Kim; Sun B Shim; Seung W Jee; Su H Lee; Su J Seo; Soo Y Choi; Yong K Kim
Journal:  Neuromolecular Med       Date:  2006       Impact factor: 3.843

Review 3.  Vascular and non-vascular contributors to memory reduction during traumatic brain injury.

Authors:  Mariam Charkviani; Nino Muradashvili; David Lominadze
Journal:  Eur J Neurosci       Date:  2019-03-12       Impact factor: 3.386

4.  Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1.

Authors:  I Dewachter; J Van Dorpe; L Smeijers; M Gilis; C Kuipéri; I Laenen; N Caluwaerts; D Moechars; F Checler; H Vanderstichele; F Van Leuven
Journal:  J Neurosci       Date:  2000-09-01       Impact factor: 6.167

5.  Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans.

Authors:  Kunihiro Uryu; Xiao-Han Chen; Dan Martinez; Kevin D Browne; Victoria E Johnson; David I Graham; Virginia M-Y Lee; John Q Trojanowski; Douglas H Smith
Journal:  Exp Neurol       Date:  2007-07-10       Impact factor: 5.330

6.  Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma.

Authors:  Xiao-Han Chen; Robert Siman; Akira Iwata; David F Meaney; John Q Trojanowski; Douglas H Smith
Journal:  Am J Pathol       Date:  2004-08       Impact factor: 4.307

7.  Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

Authors:  J H Kim; R Anwyl; Y H Suh; M B Djamgoz; M J Rowan
Journal:  J Neurosci       Date:  2001-02-15       Impact factor: 6.167

8.  Central CRF system perturbation in an Alzheimer's disease knockin mouse model.

Authors:  Qinxi Guo; Hui Zheng; Nicholas John Justice
Journal:  Neurobiol Aging       Date:  2012-02-14       Impact factor: 4.673

9.  BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism.

Authors:  Anna L Stern; Shivesh Ghura; Patrick J Gannon; Cagla Akay-Espinoza; Jessica M Phan; Alan C Yee; Robert Vassar; Benjamin B Gelman; Dennis L Kolson; Kelly L Jordan-Sciutto
Journal:  J Neurosci       Date:  2018-04-09       Impact factor: 6.167

Review 10.  Protein accumulation in traumatic brain injury.

Authors:  Douglas H Smith; Kunihiro Uryu; Kathryn E Saatman; John Q Trojanowski; Tracy K McIntosh
Journal:  Neuromolecular Med       Date:  2003       Impact factor: 3.843
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