Literature DB >> 9115408

The Yin-Yang of cobalamin biochemistry.

R Banerjee1.   

Abstract

The cobalamins are B12 cofactors with a reactive cobalt-carbon bond at their core and support the activity of two mammalian enzymes that are both medically important. The reactive organometallic bond of the cofactor can be cleaved either homolytically or heterolytically, but what determines how the enzymes control the fate of this bond?

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Year:  1997        PMID： 9115408     DOI： 10.1016/s1074-5521(97)90286-6

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  16 in total

1.  Protein-coenzyme interactions in adenosylcobalamin-dependent glutamate mutase.

Authors:  M S Huhta; H P Chen; C Hemann; C R Hille; E N Marsh
Journal:  Biochem J       Date:  2001-04-01       Impact factor: 3.857

2.  DFT analysis of co-alkyl and co-adenosyl vibrational modes in B12-cofactors.

Authors:  Pawel M Kozlowski; Tadeusz Andruniow; Andrzej A Jarzecki; Marek Z Zgierski; Thomas G Spiro
Journal:  Inorg Chem       Date:  2006-07-10       Impact factor: 5.165

3.  X-ray structural characterization of imidazolylcobalamin and histidinylcobalamin: cobalamin models for aquacobalamin bound to the B12 transporter protein transcobalamin.

Authors:  Luciana Hannibal; Scott D Bunge; Rudi van Eldik; Donald W Jacobsen; Christoph Kratky; Karl Gruber; Nicola E Brasch
Journal:  Inorg Chem       Date:  2007-04-04       Impact factor: 5.165

4.  Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria.

Authors:  D Leclerc; A Wilson; R Dumas; C Gafuik; D Song; D Watkins; H H Heng; J M Rommens; S W Scherer; D S Rosenblatt; R A Gravel
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-17       Impact factor: 11.205

5.  Reductive elimination pathway for homocysteine to methionine conversion in cobalamin-dependent methionine synthase.

Authors:  Pawel M Kozlowski; Takashi Kamachi; Manoj Kumar; Kazunari Yoshizawa
Journal:  J Biol Inorg Chem       Date:  2012-02-23       Impact factor: 3.358

6.  Functionally null mutations in patients with the cblG-variant form of methionine synthase deficiency.

Authors:  A Wilson; D Leclerc; F Saberi; E Campeau; H Y Hwang; B Shane; J A Phillips; D S Rosenblatt; R A Gravel
Journal:  Am J Hum Genet       Date:  1998-08       Impact factor: 11.025

7.  High resolution crystal structure of the methylcobalamin analogues ethylcobalamin and butylcobalamin by X-ray synchrotron diffraction.

Authors:  Luciana Hannibal; Clyde A Smith; Jessica A Smith; Armend Axhemi; Abby Miller; Sihe Wang; Nicola E Brasch; Donald W Jacobsen
Journal:  Inorg Chem       Date:  2009-07-20       Impact factor: 5.165

8.  Mercury methylation independent of the acetyl-coenzyme A pathway in sulfate-reducing bacteria.

Authors:  Eileen B Ekstrom; François M M Morel; Janina M Benoit
Journal:  Appl Environ Microbiol       Date:  2003-09       Impact factor: 4.792

9.  Liver betaine-homocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc.

Authors:  Carmen Castro; Norman S Millian; Timothy A Garrow
Journal:  Arch Biochem Biophys       Date:  2008-01-31       Impact factor: 4.013

10.  Changes in the free energy profile of glutamate mutase imparted by the mutation of an active site arginine residue to lysine.

Authors:  Anjali Patwardhan; E Neil G Marsh
Journal:  Arch Biochem Biophys       Date:  2007-01-31       Impact factor: 4.013
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