| Literature DB >> 9114427 |
R C Cooksey1, G P Morlock, S Glickman, J T Crawford.
Abstract
A commercial line probe assay kit (Inno-LiPA Rif.TB) for rapid identification of mutations in the rpoB gene associated with rifampin resistance in Mycobacterium tuberculosis was evaluated with a collection of 51 rifampin-resistant strains. Nine distinct rpoB mutations were identified. Concordances with automated sequence results for five wild-type kit probes and four probes for specific mutations were 94.1 and 100%, respectively. Overall concordance of the line probe assay kit with phenotypic rifampin susceptibility testing results was 90.2%.Entities:
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Year: 1997 PMID: 9114427 PMCID: PMC232749 DOI: 10.1128/jcm.35.5.1281-1283.1997
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948