Literature DB >> 9112748

pH, healing rate and symptom relief in acid-related diseases.

J Q Huang1, R H Hunt.   

Abstract

Suppression of gastric acid secretion is widely used and logical for the treatment of acid-related diseases. Healing of duodenal ulcer, gastric ulcer and gastroesophageal reflux disease is correlated significantly with the degree and the duration of suppression of intragastric acidity over 24 hours and with the length of the treatment. To date, proton pump inhibitors are the most effective agents among the currently available antisecretory drugs in offering the highest healing rate and fastest resolution of symptoms. Combinations of an antisecretory drug with one or more antimicrobial agents accelerate healing of peptic ulcers.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 9112748      PMCID： PMC2588990     

Source DB:  PubMed          Journal:  Yale J Biol Med        ISSN： 0044-0086


  98 in total

1.  The relationship between basal and maximum acid output in normal subjects and patients with duodenal ulcer.

Authors:  J H BARON
Journal:  Clin Sci       Date:  1963-06       Impact factor: 6.124

2.  Sensitivity of the esophageal mucosa to pH in gastroesophageal reflux disease.

Authors:  J L Smith; A R Opekun; E Larkai; D Y Graham
Journal:  Gastroenterology       Date:  1989-03       Impact factor: 22.682

Review 3.  Optimizing acid suppression for treatment of acid-related diseases.

Authors:  R H Hunt; C Cederberg; J Dent; F Halter; C Howden; I N Marks; S Rune; R P Walt
Journal:  Dig Dis Sci       Date:  1995-02       Impact factor: 3.199

4.  Double-blind comparison of pantoprazole and omeprazole for the treatment of acute duodenal ulcer.

Authors:  J A Beker; G Bianchi Porro; M A Bigard; G Delle Fave; G Devis; H Gouerou; C Maier
Journal:  Eur J Gastroenterol Hepatol       Date:  1995-05       Impact factor: 2.566

5.  Triple therapy of Helicobacter pylori infection in peptic ulcer. A 12-month follow-up study of 93 patients.

Authors:  K Seppälä; M Färkkilä; H Nuutinen; K Hakala; H Väänänen; H Rautelin; T U Kosunen
Journal:  Scand J Gastroenterol       Date:  1992-11       Impact factor: 2.423

Review 6.  The treatment of gastric ulcer with antisecretory drugs. Relationship of pharmacological effect to healing rates.

Authors:  C W Howden; D B Jones; K E Peace; D W Burget; R H Hunt
Journal:  Dig Dis Sci       Date:  1988-05       Impact factor: 3.199

7.  Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease.

Authors:  E M el-Omar; I D Penman; J E Ardill; R S Chittajallu; C Howie; K E McColl
Journal:  Gastroenterology       Date:  1995-09       Impact factor: 22.682

8.  A double-blind study of pantoprazole and omeprazole in the treatment of reflux oesophagitis: a multicentre trial.

Authors:  J Mössner; A H Hölscher; R Herz; A Schneider
Journal:  Aliment Pharmacol Ther       Date:  1995-06       Impact factor: 8.171

9.  Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: randomised controlled trial.

Authors:  S W Hosking; T K Ling; S C Chung; M Y Yung; A F Cheng; J J Sung; A K Li
Journal:  Lancet       Date:  1994-02-26       Impact factor: 79.321

Review 10.  Inflammation, acid and ulcers.

Authors:  M J Muller; R H Hunt
Journal:  Yale J Biol Med       Date:  1994 May-Aug
View more
  10 in total

Review 1.  Acid sensing by visceral afferent neurones.

Authors:  P Holzer
Journal:  Acta Physiol (Oxf)       Date:  2011-01       Impact factor: 6.311

2.  Anilinomethylrhodamines: pH sensitive probes with tunable photophysical properties by substituent effect.

Authors:  Quinn A Best; Chuangjun Liu; Paul D van Hoveln; Matthew E McCarroll; Colleen N Scott
Journal:  J Org Chem       Date:  2013-10-09       Impact factor: 4.354

3.  Acid peptic diseases: pharmacological approach to treatment.

Authors:  Alex Mejia; Walter K Kraft
Journal:  Expert Rev Clin Pharmacol       Date:  2009-05       Impact factor: 5.045

4.  Efficacy of a proton pump inhibitor given in the early postoperative period to relieve symptoms of hiatal hernia after open heart surgery.

Authors:  Mitsumasa Hata; Motomi Shiono; Hisakuni Sekino; Hidekazu Furukawa; Akira Sezai; Mitsuru Iida; Isamu Yoshitake; Tsutomu Hattori; Shinji Wakui; Makoto Taoka; Nanao Negishi; Yukiyasu Sezai
Journal:  Surg Today       Date:  2006       Impact factor: 2.549

5.  Significant enhancement of gastric mucin content after rabeprazole administration: its potential clinical significance in acid-related disorders.

Authors:  T Skoczylas; I Sarosiek; S Sostarich; C McElhinney; S Durham; J Sarosiek
Journal:  Dig Dis Sci       Date:  2003-02       Impact factor: 3.199

6.  Interchangeable Use of Proton Pump Inhibitors Based on Relative Potency.

Authors:  David Y Graham; Aylin Tansel
Journal:  Clin Gastroenterol Hepatol       Date:  2017-09-28       Impact factor: 11.382

Review 7.  Acid-sensing ion channels in gastrointestinal function.

Authors:  Peter Holzer
Journal:  Neuropharmacology       Date:  2015-01-09       Impact factor: 5.250

Review 8.  25 Years of Proton Pump Inhibitors: A Comprehensive Review.

Authors:  Daniel S Strand; Daejin Kim; David A Peura
Journal:  Gut Liver       Date:  2017-01-15       Impact factor: 4.519

Review 9.  Proton Pump Inhibitors and Oncologic Treatment Efficacy: A Practical Review of the Literature for Oncologists.

Authors:  Angel A T Uchiyama; Pedro A I A Silva; Moisés S M Lopes; Cheng T Yen; Eliza D Ricardo; Taciana Mutão; Jefferson R Pimenta; Larissa M Machado; Denis S Shimba; Renata D Peixoto
Journal:  Curr Oncol       Date:  2021-02-03       Impact factor: 3.677

10.  A collection of the etiological theories, characteristics, and observations/phenomena of peptic ulcers in existing data.

Authors:  Simon X M Dong; Connie C Y Chang; Katelynn J Rowe
Journal:  Data Brief       Date:  2018-05-16
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.