Literature DB >> 9108931

Problems and prospects of developing effective therapy for common cold viruses.

S L Johnston1.   

Abstract

No effective treatment for common colds has yet been developed. Combination antiviral and anti-inflammatory therapies are the best hope for intervention after the onset of symptoms. Prophylaxis, especially in the form of vaccination, would have a major impact in disease prevention. These approaches offer new avenues for treating populations at risk and are of particular significance to those with asthma or chronic bronchitis.

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Year:  1997        PMID： 9108931      PMCID： PMC7133329          DOI： 10.1016/S0966-842X(96)10082-2

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  54 in total

1.  Kinins are generated during experimental rhinovirus colds.

Authors:  R M Naclerio; D Proud; L M Lichtenstein; A Kagey-Sobotka; J O Hendley; J Sorrentino; J M Gwaltney
Journal:  J Infect Dis       Date:  1988-01       Impact factor: 5.226

Review 2.  The picornaviral 3C proteinases: cysteine nucleophiles in serine proteinase folds.

Authors:  B A Malcolm
Journal:  Protein Sci       Date:  1995-08       Impact factor: 6.725

3.  Is histamine responsible for the symptoms of rhinovirus colds? A look at the inflammatory mediators following infection.

Authors:  R M Naclerio; D Proud; A Kagey-Sobotka; L M Lichtenstein; J O Hendley; J M Gwaltney
Journal:  Pediatr Infect Dis J       Date:  1988-03       Impact factor: 2.129

4.  Effectiveness and safety of intranasal ipratropium bromide in common colds. A randomized, double-blind, placebo-controlled trial.

Authors:  F G Hayden; L Diamond; P B Wood; D C Korts; M T Wecker
Journal:  Ann Intern Med       Date:  1996-07-15       Impact factor: 25.391

5.  Treatment of acute, episodic asthma in preschool children using intermittent high dose inhaled steroids at home.

Authors:  N M Wilson; M Silverman
Journal:  Arch Dis Child       Date:  1990-04       Impact factor: 3.791

6.  The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis.

Authors:  S L Johnston; P K Pattemore; G Sanderson; S Smith; M J Campbell; L K Josephs; A Cunningham; B S Robinson; S H Myint; M E Ward; D A Tyrrell; S T Holgate
Journal:  Am J Respir Crit Care Med       Date:  1996-09       Impact factor: 21.405

7.  Intranasally and orally administered antihistamine treatment of experimental rhinovirus colds.

Authors:  M J Gaffey; J M Gwaltney; A Sastre; W E Dressler; J V Sorrentino; F G Hayden
Journal:  Am Rev Respir Dis       Date:  1987-09

8.  Heterologous protection against influenza by injection of DNA encoding a viral protein.

Authors:  J B Ulmer; J J Donnelly; S E Parker; G H Rhodes; P L Felgner; V J Dwarki; S H Gromkowski; R R Deck; C M DeWitt; A Friedman
Journal:  Science       Date:  1993-03-19       Impact factor: 47.728

9.  Structure determination of antiviral compound SCH 38057 complexed with human rhinovirus 14.

Authors:  A Zhang; R G Nanni; T Li; G F Arnold; D A Oren; A Jacobo-Molina; R L Williams; G Kamer; D A Rubenstein; Y Li
Journal:  J Mol Biol       Date:  1993-04-05       Impact factor: 5.469

10.  A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon.

Authors:  B A Hassel; A Zhou; C Sotomayor; A Maran; R H Silverman
Journal:  EMBO J       Date:  1993-08       Impact factor: 11.598
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  5 in total

1.  The relationship between the frequency of the common cold and the activities of natural killer cells.

Authors:  M Xu; T Muto; T Yabe; F Nagao; Y Fukuwatart; K Okumura
Journal:  Environ Health Prev Med       Date:  2000-01       Impact factor: 3.674

2.  Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial.

Authors:  M Jawad; R Schoop; A Suter; P Klein; R Eccles
Journal:  Evid Based Complement Alternat Med       Date:  2012-09-16       Impact factor: 2.629

Review 3.  Mechanisms of asthma exacerbation.

Authors:  S L Johnston
Journal:  Clin Exp Allergy       Date:  1998-11       Impact factor: 5.018

Review 4.  Viruses and asthma.

Authors:  S L Johnston
Journal:  Allergy       Date:  1998-10       Impact factor: 13.146

Review 5.  Efficacy and safety of Echinaforce® in respiratory tract infections.

Authors:  Andreas Schapowal
Journal:  Wien Med Wochenschr       Date:  2012-12-20
  5 in total

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