Literature DB >> 9105267

Capillary electrophoresis system for hemoglobin A1c determinations evaluated.

C J Doelman1, C W Siebelder, W A Nijhof, C W Weykamp, J Janssens, T J Penders.   

Abstract

Hb A1c is the analyte of choice for monitoring metabolic control in patients with diabetes mellitus. Here we present a new analytical technique for measuring Hb A1c, capillary electrophoresis. The Hb A1c determination is not influenced by the labile Hb A1c fraction or by carbamylated or acetylated hemoglobin derivatives. Also, hemoglobin variants (Hb F, Hb S, and Hb C) do not interfere. This new application of capillary electrophoresis seems to be a valuable analytical tool for measuring Hb A1c in the clinical laboratory.

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Year:  1997        PMID： 9105267

Source DB:  PubMed          Journal:  Clin Chem        ISSN： 0009-9147            Impact factor:   8.327


  3 in total

Review 1.  Clinical applications of capillary electrophoresis. Status at the new millennium.

Authors:  M A Jenkins
Journal:  Mol Biotechnol       Date:  2000-07       Impact factor: 2.695

2.  Hematological and Molecular Characterization of Hb J-Buda [α61(E10)Lys → Asn, AAG > AAT].

Authors:  Sitthichai Panyasai; Nopphadol Permsripong; Kanokwan Jaiping; Pisuttinee Khantarag; Sakorn Pornprasert
Journal:  Indian J Hematol Blood Transfus       Date:  2016-01-23       Impact factor: 0.900

3.  Evaluation of hemoglobin A1c measurement by Capillarys 2 electrophoresis for detection of abnormal glucose tolerance in African immigrants to the United States.

Authors:  Zhen Zhao; Jeffrey Basilio; Steven Hanson; Randie R Little; Anne E Sumner; David B Sacks
Journal:  Clin Chim Acta       Date:  2015-04-08       Impact factor: 3.786
  3 in total

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