| Literature DB >> 910158 |
C J Grubbs, R C Moon, R A Squire, G M Farrow, S F Stinson, D G Goodman, C C Brown, M B Sporn.
Abstract
Transitional cell carcinoma was induced in the bladders of male Fischer rats by 12 oral doses of the carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine. Feeding of 13-cis-retinoic acid after completion of carcinogen treatment diminished the number and severity of cancers and other proliferative lesions of the bladder.Entities:
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Year: 1977 PMID: 910158 DOI: 10.1126/science.910158
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728