Literature DB >> 9099798

Generation of antibody diversity in rabbits.

K L Knight1, C R Winstead.   

Abstract

Most rabbit B lymphocytes use the same VH gene in V(D)J gene rearrangements and undergo somatic diversification by gene conversion and hypermutation. Recent experiments have shown that V(D)J genes in essentially all rabbit B cells diversify shortly after birth and that this diversification occurs in the gut-associated lymphoid tissue. Still to be determined is whether this diversification is developmentally programmed or is driven by exogenous microbial antigens.

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Year:  1997        PMID: 9099798     DOI: 10.1016/s0952-7915(97)80140-9

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  8 in total

1.  Antibodies against non-immunizing antigens derived from a large immune scFv library.

Authors:  Sung Ah Moon; Min Kyung Ki; Sungyoung Lee; Mi-Lim Hong; Misook Kim; Sungsub Kim; Junho Chung; Sue Goo Rhee; Hyunbo Shim
Journal:  Mol Cells       Date:  2011-04-15       Impact factor: 5.034

Review 2.  Evolution of B cell immunity.

Authors:  David Parra; Fumio Takizawa; J Oriol Sunyer
Journal:  Annu Rev Anim Biosci       Date:  2013-01       Impact factor: 8.923

3.  Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility.

Authors:  Haiyong Peng; Thomas Nerreter; Jing Chang; Junpeng Qi; Xiuling Li; Pabalu Karunadharma; Gustavo J Martinez; Mohammad Fallahi; Jo Soden; Jim Freeth; Roger R Beerli; Ulf Grawunder; Michael Hudecek; Christoph Rader
Journal:  J Mol Biol       Date:  2017-08-14       Impact factor: 5.469

4.  Somatically diversified and proliferating transitional B cells: implications for peripheral B cell homeostasis.

Authors:  Venkata A Yeramilli; Katherine L Knight
Journal:  J Immunol       Date:  2011-04-27       Impact factor: 5.422

5.  Rational HIV immunogen design to target specific germline B cell receptors.

Authors:  Joseph Jardine; Jean-Philippe Julien; Sergey Menis; Takayuki Ota; Oleksandr Kalyuzhniy; Andrew McGuire; Devin Sok; Po-Ssu Huang; Skye MacPherson; Meaghan Jones; Travis Nieusma; John Mathison; David Baker; Andrew B Ward; Dennis R Burton; Leonidas Stamatatos; David Nemazee; Ian A Wilson; William R Schief
Journal:  Science       Date:  2013-03-28       Impact factor: 47.728

6.  NHEJ-deficient DT40 cells have increased levels of immunoglobulin gene conversion: evidence for a double strand break intermediate.

Authors:  Ephraim S Tang; Alberto Martin
Journal:  Nucleic Acids Res       Date:  2006-11-16       Impact factor: 16.971

7.  Assessment of the rabbit as a wildlife reservoir of bovine viral diarrhea virus: serological analysis and generation of trans-placentally infected offspring.

Authors:  Dawn M Grant; Mark P Dagleish; Claudia Bachofen; Brian Boag; David Deane; Ann Percival; Ruth N Zadoks; George C Russell
Journal:  Front Microbiol       Date:  2015-09-23       Impact factor: 5.640

Review 8.  Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination.

Authors:  Claudia Müller; Rafał Hrynkiewicz; Dominika Bębnowska; Jaime Maldonado; Massimiliano Baratelli; Bernd Köllner; Paulina Niedźwiedzka-Rystwej
Journal:  Vaccines (Basel)       Date:  2021-03-13
  8 in total

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