Literature DB >> 909611

Influence of enkephalin on K+-evoked efflux of putative neurotransmitters in rat brain. Selective inhibition of acetylcholine and dopamine release.

N Subramanian, P Mitznegg, W Sprügel, W Domschke, S Domschke, E Wünsch, L Demling.   

Abstract

In rat brain slices preincubated with various radiolabelled putative neurotransmitters, methionine-enkephalin diminished the potassium-evoked release of dopamine and acetylcholine. The effect was antagonised by naloxone. The potassium-induced effux of three other neurotransmitters, histamine, 5-hydroxy-tryptamine and gamma-aminobutyric acid, were unaffected by methionine-enkephalin. A probable physiological function for the endogenous ligands in specifically affecting the catecholaminergic and cholinergic transmission is suggested.

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Year:  1977        PMID： 909611     DOI： 10.1007/bf00498558

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  14 in total

1.  Enkephalin-induced inhibition of cortical neurones and the lack of this effect in morphine tolerant/dependent rats.

Authors:  W Zieglgänsberger; J P Fry; A Herz; L Moroder; E Wünsch
Journal:  Brain Res       Date:  1976-10-08       Impact factor: 3.252

2.  Calcium-dependent release of radiolabeled catecholamines and serotonin from rat brain synaptosomes in a superfusion system.

Authors:  A H Mulder; W B van den Berg; J C Stoof
Journal:  Brain Res       Date:  1975-12-05       Impact factor: 3.252

3.  Effects of morphine on kinetics of 14C-dopamine in rat striatal slices.

Authors:  B Celsen; K Kuschinsky
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

4.  Inhibition by morphine of the release of [14c]acetylcholine from rat brain cortex slices.

Authors:  M Sharkawi; M P Schulman
Journal:  J Pharm Pharmacol       Date:  1969-08       Impact factor: 3.765

5.  Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake.

Authors:  A H Mulder; H I Yamamura; M J Kuhar; S H Snyder
Journal:  Brain Res       Date:  1974-04-19       Impact factor: 3.252

6.  Enkephalin: a potential modulator of noradrenaline release in rat brain.

Authors:  H D Taube; E Borowski; T Endo; K Starke
Journal:  Eur J Pharmacol       Date:  1976-08       Impact factor: 4.432

7.  Identification of two related pentapeptides from the brain with potent opiate agonist activity.

Authors:  J Hughes; T W Smith; H W Kosterlitz; L A Fothergill; B A Morgan; H R Morris
Journal:  Nature       Date:  1975-12-18       Impact factor: 49.962

8.  Comparative effects of opiate agonists methadone, levorphanol, and their isomers on the release of cortical ACh in vivo and in vitro.

Authors:  K Jhamandas; V Hron; M Sutak
Journal:  Can J Physiol Pharmacol       Date:  1975-08       Impact factor: 2.273

9.  Influence of morphine and naloxone on the release of noradrenaline from rat cerebellar cortex slices.

Authors:  H Montel; K Starke; H D Taube
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

10.  Potassium-induced release of tritiated histamine from rat brain tissue slices.

Authors:  N Subramanian; A H Mulder
Journal:  Eur J Pharmacol       Date:  1976-01       Impact factor: 4.432
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  12 in total

1.  Specific opioid-amphetamine interactions in the caudate putamen.

Authors:  S K Woo; R J Hitzemann; H H Loh
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

Review 2.  Comparative aspects of opioid-dopamine interaction.

Authors:  G B Stefano
Journal:  Cell Mol Neurobiol       Date:  1982-09       Impact factor: 5.046

3.  Effects of naloxone on methamphetamine and apomorphine stereotypy and on haloperidol catalepsy in rats.

Authors:  J J Balsara; N V Nandal; N P Burte; J H Jadhav; A G Chandorkar
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

4.  Effect of in vivo administration of naloxone on ATP-ase's enzyme systems of synaptic plasma membranes from rat cerebral cortex.

Authors:  A Gorini; A Rancati; A D'Angelo; E Devecchi; R F Villa
Journal:  Neurochem Res       Date:  2000-06       Impact factor: 3.996

5.  Investigation of action of enkephalin on the spontaneous and evoked release of acetylcholine from rat cortical and striatal slices.

Authors:  K Jhamandas; J Elliott
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739

6.  Action of enkephalin analogues and morphine on brain acetylcholine release: differential reversal by naloxone and an opiate pentapeptide.

Authors:  K Jhamandas; M Sutak
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739

7.  Release of endogenous dopamine from rat isolated striatum: effect of clorgyline and (-)-deprenyl.

Authors:  L G Hársing; E S Vizi
Journal:  Br J Pharmacol       Date:  1984-11       Impact factor: 8.739

8.  Glutamate-evoked release of endogenous brain dopamine: inhibition by an excitatory amino acid antagonist and an enkephalin analogue.

Authors:  K Jhamandas; M Marien
Journal:  Br J Pharmacol       Date:  1987-04       Impact factor: 8.739

9.  The effect of naloxone on opioid-induced inhibition and facilitation of acetylcholine release in brain slices.

Authors:  L Beani; C Bianchi; A Siniscalchi
Journal:  Br J Pharmacol       Date:  1982-07       Impact factor: 8.739

10.  The effect of enkephalins and of beta-endorphin on the hypertensive response to physostigmine in the rat.

Authors:  V M Varagić; V Stojanović
Journal:  Br J Pharmacol       Date:  1987-09       Impact factor: 8.739
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