Literature DB >> 9094698

The poly(C) region affects progression of encephalomyocarditis virus infection in Langerhans' islets but not in the myocardium.

A Zimmermann1, A Botta, G Arnold, H J Eggers, B Nelsen-Salz.   

Abstract

The diabetogenic variant PV2 of encephalomyocarditis virus was cloned, and three recombinants differing in their 5' poly(C) tracts were analyzed. It is shown that the poly(C) region is not essential for infectivity in mice but does influence the virus load and degree of pathological lesions within the Langerhans' islets but not in the myocardium.

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Year:  1997        PMID： 9094698      PMCID： PMC191573     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

Review 1.  Encephalomyocarditis virus-induced diabetes mellitus in mice: model of viral pathogenesis.

Authors:  G W Jordan; S H Cohen
Journal:  Rev Infect Dis       Date:  1987 Sep-Oct

2.  Poly(C) in animal viral RNAs.

Authors:  F Brown; J Newman; J Stott; A Porter; D Frisby; C Newton; N Carey; P Fellner
Journal:  Nature       Date:  1974-09-27       Impact factor: 49.962

3.  Differing attachment of diabetogenic and nondiabetogenic variants of encephalomyocarditis virus to beta-cells.

Authors:  P E Kaptur; D C Thomas; D J Giron
Journal:  Diabetes       Date:  1989-09       Impact factor: 9.461

4.  Encephalomyocarditis virus and diabetes mellitus: studies on virus mutants in susceptible and non-susceptible mice.

Authors:  J P Kruppenbacher; T Mertens; H Müntefering; H J Eggers
Journal:  J Gen Virol       Date:  1985-04       Impact factor: 3.891

5.  Cloning and synthesis of infectious cardiovirus RNAs containing short, discrete poly(C) tracts.

Authors:  G M Duke; A C Palmenberg
Journal:  J Virol       Date:  1989-04       Impact factor: 5.103

6.  The role of interferon in virus-induced diabetes.

Authors:  J W Yoon; C Y Cha; G W Jordan
Journal:  J Infect Dis       Date:  1983-01       Impact factor: 5.226

7.  Relationship of interferon-inducing particle phenotype to encephalomyocarditis virus-induced diabetes mellitus.

Authors:  S H Cohen; V Bolton; G W Jordan
Journal:  Infect Immun       Date:  1983-11       Impact factor: 3.441

8.  Inhibition of virus-induced diabetes mellitus by interferon is influenced by the host strain.

Authors:  D J Giron; S J Cohen; S P Lyons; C H Wharton; D R Cerutis
Journal:  Proc Soc Exp Biol Med       Date:  1983-07

9.  Analysis of sequence and pathogenic properties of two variants of encephalomyocarditis virus differing in a single amino acid in VP1.

Authors:  B Nelsen-Salz; A Zimmermann; S Wickert; G Arnold; A Botta; H J Eggers; J P Kruppenbacher
Journal:  Virus Res       Date:  1996-04       Impact factor: 3.303

10.  Virus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus.

Authors:  J W Yoon; P R McClintock; T Onodera; A L Notkins
Journal:  J Exp Med       Date:  1980-10-01       Impact factor: 14.307
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  3 in total

Review 1.  Sarcomatoid carcinoma of the bladder after simultaneous kidney-pancreas transplant: a case report and review of the literature.

Authors:  Patrick H McCrea; Michelle Chang; Gregory Bailley; Michele Molinari
Journal:  BMJ Case Rep       Date:  2012-04-28

2.  A wild-type porcine encephalomyocarditis virus containing a short poly(C) tract is pathogenic to mice, pigs, and cynomolgus macaques.

Authors:  Rebecca LaRue; Suzanne Myers; Laurie Brewer; Daniel P Shaw; Corrie Brown; Bruce S Seal; M Kariuki Njenga
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

Review 3.  The long-lasting enigma of polycytidine (polyC) tract.

Authors:  Velia Penza; Stephen J Russell; Autumn J Schulze
Journal:  PLoS Pathog       Date:  2021-08-04       Impact factor: 6.823
  3 in total

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