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Literature DB >> 9089712

A color spot test for the detection of Kryptofix 2.2.2 in [18F]FDG preparations.

Abstract

A color spot test is described that can confirm the absence of Kryptofix 2.2.2 in 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) in less than 5 min. Pretreated strips of plastic-backed silica gel 60 thin-layer chromatographic medium, saturated with iodoplatinate reagent, are over-spotted with separate droplets of final product [18F]FDG and Kryptofix standard solutions. A blue-black circular spot is clearly visible at Kryptofix concentrations as low as 2 micrograms/mL.

Entities: Chemical

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Year: 1997 PMID： 9089712 DOI： 10.1016/s0969-8051(96)00212-0

Source DB: PubMed Journal: Nucl Med Biol ISSN： 0969-8051 Impact factor: 2.408

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Cited

13 in total

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10. Synthesis of Clinical-Grade [(18)F]-Fluoroestradiol as a Surrogate PET Biomarker for the Evaluation of Estrogen Receptor-Targeting Therapeutic Drug.

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A color spot test for the detection of Kryptofix 2.2.2 in [18F]FDG preparations.

1. Automated radiosynthesis of [(18)F]ML-10, a PET radiotracer dedicated to apoptosis imaging, on a TRACERLab FX-FN module.

2. A practical, automated synthesis of meta-[(18)F]fluorobenzylguanidine for clinical use.

3. Synthesis, quality control and determination of metallic impurities in ¹⁸F-fludeoxyglucose production process.

4. Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [¹⁰F]ICF01006, a highly promising melanoma PET tracer.

5. Fully automated radiosynthesis of 2-[18F]fludarabine for PET imaging of low-grade lymphoma.

6. Automated synthesis of 18F analogue of paclitaxel (PAC): [18F]Paclitaxel (FPAC).

7. Studies into radiolytic decomposition of fluorine-18 labeled radiopharmaceuticals for positron emission tomography.

8. Automated production of [¹⁸F]VAT suitable for clinical PET study of vesicular acetylcholine transporter.

9. Development of a Fluorinated Analogue of Erlotinib for PET Imaging of EGFR Mutation-Positive NSCLC.

10. Synthesis of Clinical-Grade [(18)F]-Fluoroestradiol as a Surrogate PET Biomarker for the Evaluation of Estrogen Receptor-Targeting Therapeutic Drug.