C Chevalet1, J Gouzy, M SanCristobal-Gaudy. 1. Laboratoire de Génétique Cellulaire, Institut National de la Recherche Agronomique BP 27, Tolosan, France. chevalet@toulouse.inra.fr
Abstract
MOTIVATION: Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise. RESULTS: An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.
MOTIVATION: Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise. RESULTS: An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.
Authors: A K Fridolfsson; T Hori; A K Winterø; M Fredholm; M Yerle; A Robic; L Andersson; H Ellegren Journal: Mamm Genome Date: 1997-12 Impact factor: 2.957