Coordinating a large multicentered HIV research project.

Coordinating a large multicentered pediatric HIV clinical research study is particularly challenging for nurses. The cohort of patients and their families face multiple stressors, which make recruitment and compliance difficult. Additionally, when many departments within the institution are involved, coordination is often problematic. Ethical issues sometimes arise. Nurses must find ways to adapt what they learn from the study to their nursing practice. The nurse coordinators of the Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV (P2C2HIV) study discuss the unique challenges of such a project and the various strategies for successful completion.