Literature DB >> 22999994

Recruitment and retention strategies in a clinical trial for children with chronic hepatitis C infection.

Aparna Roy1, Whitney Lieb, Beth Garrett, Marcia Hodik, Ann Klipsch, Melissa Young, Bruce Barton, Kathleen B Schwarz.   

Abstract

Successful strategies for recruitment and retention (R & R) in pediatric trials are needed. The purpose of our study was to analyze the effectiveness of R&R in a trial for children with hepatitis C. Recruitment strategies were (1) Initial (months 0-12) and (2) extra effort (months 13-18). Initial strategies enrolled 70/114 (61%) of patients. Extra effort strategies included: (1) radio broadcasts, (2) contact with adult hepatologists, (3) dissemination of study material and (4) modification of the exclusion criteria. The overall retention rate was 84% at 2 years. Lessons learned will be valuable in designing future pediatric trials.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22999994      PMCID： PMC3540171          DOI： 10.1016/j.pedn.2012.08.006

Source DB:  PubMed          Journal:  J Pediatr Nurs        ISSN： 0882-5963            Impact factor:   2.145


  16 in total

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Review 4.  Stigma in the context of hepatitis C: concept analysis.

Authors:  Gail Butt
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Review 6.  Children with hepatitis C.

Authors:  Maureen M Jonas
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8.  Recombinant alfa-interferon plus ribavirin therapy in children and adolescents with chronic hepatitis C.

Authors:  Stefan Wirth; Thomas Lang; Stephan Gehring; Patrick Gerner
Journal:  Hepatology       Date:  2002-11       Impact factor: 17.425

9.  Design of the PEDS-C trial: pegylated interferon +/- ribavirin for children with chronic hepatitis C viral infection.

Authors:  Karen F Murray; James R Rodrigue; Regino P González-Peralta; John Shepherd; Bruce A Barton; Patricia R Robuck; Kathleen B Schwarz
Journal:  Clin Trials       Date:  2007       Impact factor: 2.486

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