Literature DB >> 9084760

Cra and the control of carbon flux via metabolic pathways.

T M Ramseier1.   

Abstract

The catabolite repressor-activator (Cra) protein controls the direction of carbon flux through metabolic pathways in enteric bacteria. Cra binds to the control regions of target genes and exerts a negative effect on the expression of genes encoding glycolytic and Entner-Doudoroff enzymes, while exerting a positive effect on genes encoding Krebs cycle, glyoxylate shunt and gluconeogenic enzymes. Cra mediates cyclic AMP-independent catabolite repression of positively Cra-regulated genes and catabolite activation of negatively Cra-controlled genes.

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Year:  1996        PMID: 9084760     DOI: 10.1016/0923-2508(96)84003-4

Source DB:  PubMed          Journal:  Res Microbiol        ISSN: 0923-2508            Impact factor:   3.992


  33 in total

Review 1.  Comparative genomic reconstruction of transcriptional regulatory networks in bacteria.

Authors:  Dmitry A Rodionov
Journal:  Chem Rev       Date:  2007-07-18       Impact factor: 60.622

2.  Global transcription and metabolic flux analysis of Escherichia coli in glucose-limited fed-batch cultivations.

Authors:  K Lemuth; T Hardiman; S Winter; D Pfeiffer; M A Keller; S Lange; M Reuss; R D Schmid; M Siemann-Herzberg
Journal:  Appl Environ Microbiol       Date:  2008-09-19       Impact factor: 4.792

3.  Cooperative interaction between Cra and Fnr in the regulation of the cydAB operon of Escherichia coli.

Authors:  T M Ramseier; S Y Chien; M H Saier
Journal:  Curr Microbiol       Date:  1996-10       Impact factor: 2.188

4.  Functioning of a metabolic flux sensor in Escherichia coli.

Authors:  Karl Kochanowski; Benjamin Volkmer; Luca Gerosa; Bart R Haverkorn van Rijsewijk; Alexander Schmidt; Matthias Heinemann
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-31       Impact factor: 11.205

5.  The interacting Cra and KdpE regulators are involved in the expression of multiple virulence factors in enterohemorrhagic Escherichia coli.

Authors:  Jacqueline W Njoroge; Charley Gruber; Vanessa Sperandio
Journal:  J Bacteriol       Date:  2013-03-22       Impact factor: 3.490

6.  Appetite of an epiphyte: quantitative monitoring of bacterial sugar consumption in the phyllosphere.

Authors:  J H Leveau; S E Lindow
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

Review 7.  Coordination of microbial metabolism.

Authors:  Victor Chubukov; Luca Gerosa; Karl Kochanowski; Uwe Sauer
Journal:  Nat Rev Microbiol       Date:  2014-03-24       Impact factor: 60.633

8.  Impact of global transcriptional regulation by ArcA, ArcB, Cra, Crp, Cya, Fnr, and Mlc on glucose catabolism in Escherichia coli.

Authors:  Annik Perrenoud; Uwe Sauer
Journal:  J Bacteriol       Date:  2005-05       Impact factor: 3.490

9.  A homolog of CcpA mediates catabolite control in Listeria monocytogenes but not carbon source regulation of virulence genes.

Authors:  J Behari; P Youngman
Journal:  J Bacteriol       Date:  1998-12       Impact factor: 3.490

10.  Co-expression of Skp and FkpA chaperones improves cell viability and alters the global expression of stress response genes during scFvD1.3 production.

Authors:  Dave Siak-Wei Ow; Denis Yong-Xiang Lim; Peter Morin Nissom; Andrea Camattari; Victor Vai-Tak Wong
Journal:  Microb Cell Fact       Date:  2010-04-13       Impact factor: 5.328

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