Literature DB >> 908143

Activities of bone and liver alkaline phosphatases in serum in health and disease.

K B Whitaker, L G Whitby, D W Moss.   

Abstract

A heat-inactivation method for determining absolute activities of liver and bone alkaline phosphatases in serum has been applied extensively in routine diagnosis. Values for each isoenzyme in healthy individuals of different ages are reported together with results obtained in various diseases. Data from normal subjects show that bone alkaline phosphatase contributes about half the total alkaline phosphatase activity in adults. Liver phosphatase shows a slight increase with age. The method is also able to detect reliably the presence of carcinoplacental isoenzymes.

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Year:  1977        PMID： 908143     DOI： 10.1016/0009-8981(77)90281-9

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  9 in total

1.  Quantitative method for determining serum alkaline phosphatase isoenzyme activity II. Development and clinical application of method for measuring four serum alkaline phosphatase isoenzymes.

Authors:  M D Shephard; M J Peake; R N Walmsley
Journal:  J Clin Pathol       Date:  1986-09       Impact factor: 3.411

2.  Premature loss of bone in chronic anorexia nervosa.

Authors:  B J Matthews; J H Lacey; H Cleeve
Journal:  Br Med J (Clin Res Ed)       Date:  1985-05-11

3.  Frequency distribution and 'reference values' of plasma alkaline phosphatase (EC 3.1.3.1) activity in the adult population of a Scottish new town.

Authors:  M D Gardner; R Scott
Journal:  J Clin Pathol       Date:  1978-12       Impact factor: 3.411

4.  Effects of exposure to cadmium on calcium metabolism: a population study.

Authors:  J Staessen; A Amery; A Bernard; P Bruaux; J P Buchet; F Claeys; P De Plaen; G Ducoffre; R Fagard; R R Lauwerys
Journal:  Br J Ind Med       Date:  1991-10

5.  Pamidronate is effective for Paget's disease of bone refractory to conventional therapy.

Authors:  S J Wimalawansa; R D Gunasekera
Journal:  Calcif Tissue Int       Date:  1993-10       Impact factor: 4.333

6.  Determinants of variation in plasma alkaline phosphatase activity: a twin study.

Authors:  J B Whitfield; N G Martin
Journal:  Am J Hum Genet       Date:  1983-09       Impact factor: 11.025

7.  Serum concentrations of vitamin D metabolites in untreated tuberculosis.

Authors:  P D Davies; R C Brown; J S Woodhead
Journal:  Thorax       Date:  1985-03       Impact factor: 9.139

Review 8.  Bone biomarker for the clinical assessment of osteoporosis: recent developments and future perspectives.

Authors:  Tsung-Rong Kuo; Chih-Hwa Chen
Journal:  Biomark Res       Date:  2017-05-18

9.  Measurement of high molecular weight forms of enzymes in serum in the detection of hepatic metastases of colorectal cancer.

Authors:  O J Traynor; C B Wood; Z O Echetebu; K B Whitaker; D W Moss
Journal:  Br J Cancer       Date:  1986-04       Impact factor: 7.640
  9 in total

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