Literature DB >> 9071568

Comparative genomic hybridization study of primary neuroblastoma tumors. United Kingdom Children's Cancer Study Group.

M Lastowska1, E Nacheva, A McGuckin, A Curtis, C Grace, A Pearson, N Bown.   

Abstract

Neuroblastoma tumors show a complex interaction of genetic abnormalities, among which some are of significant prognostic importance; however, analysis of chromosome changes in this tumor is often unsuccessful. Twenty primary tumors were studied by comparative genomic hybridization (CGH), and abnormalities were found in 19. While these changes included deletions of chromosome arm Ip (45%) and MYCN oncogene amplification (30%), gains of chromosome 17 material were much more frequent (75%). We also found evidence in two cases of a new amplification site at band 2p23.

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Year:  1997        PMID： 9071568

Source DB:  PubMed          Journal:  Genes Chromosomes Cancer        ISSN： 1045-2257            Impact factor:   5.006


  10 in total

Review 1.  DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.

Authors:  S Knuutila; A M Björkqvist; K Autio; M Tarkkanen; M Wolf; O Monni; J Szymanska; M L Larramendy; J Tapper; H Pere; W El-Rifai; S Hemmer; V M Wasenius; V Vidgren; Y Zhu
Journal:  Am J Pathol       Date:  1998-05       Impact factor: 4.307

Review 2.  Neuroblastoma tumour genetics: clinical and biological aspects.

Authors:  N Bown
Journal:  J Clin Pathol       Date:  2001-12       Impact factor: 3.411

Review 3.  The connections between neural crest development and neuroblastoma.

Authors:  Manrong Jiang; Jennifer Stanke; Jill M Lahti
Journal:  Curr Top Dev Biol       Date:  2011       Impact factor: 4.897

4.  Classification of arrayCGH data using fused SVM.

Authors:  Franck Rapaport; Emmanuel Barillot; Jean-Philippe Vert
Journal:  Bioinformatics       Date:  2008-07-01       Impact factor: 6.937

5.  Numerical and structural aberrations in advanced neuroblastoma tumours by CGH analysis; survival correlates with chromosome 17 status.

Authors:  C L Cunsolo; M P Bicocchi; A R Petti; G P Tonini
Journal:  Br J Cancer       Date:  2000-11       Impact factor: 7.640

6.  Neuroblastomas with chromosome 11q loss and single copy MYCN comprise a biologically distinct group of tumours with adverse prognosis.

Authors:  M E Luttikhuis; J E Powell; S A Rees; T Genus; S Chughtai; P Ramani; J R Mann; C M McConville
Journal:  Br J Cancer       Date:  2001-08-17       Impact factor: 7.640

Review 7.  Comparative genomic hybridization and chromosomal instability in solid tumours.

Authors:  P H Rooney; G I Murray; D A Stevenson; N E Haites; J Cassidy; H L McLeod
Journal:  Br J Cancer       Date:  1999-05       Impact factor: 7.640

8.  The genetic tumor background is an important determinant for heterogeneous MYCN-amplified neuroblastoma.

Authors:  Dominik Bogen; Clemens Brunner; Diana Walder; Andrea Ziegler; Reza Abbasi; Ruth L Ladenstein; Rosa Noguera; Tommy Martinsson; Gabriele Amann; Freimut H Schilling; Marek Ussowicz; Martin Benesch; Peter F Ambros; Inge M Ambros
Journal:  Int J Cancer       Date:  2016-03-22       Impact factor: 7.396

9.  Comparative genomic hybridization and telomerase activity analysis identify two biologically different groups of 4s neuroblastomas.

Authors:  C Brinkschmidt; C Poremba; H Christiansen; R Simon; K L Schäfer; H J Terpe; F Lampert; W Boecker; B Dockhorn-Dworniczak
Journal:  Br J Cancer       Date:  1998-06       Impact factor: 7.640

10.  Fluorescence in situ hybridization techniques for the rapid detection of genetic prognostic factors in neuroblastoma. United Kingdom Children's Cancer Study Group.

Authors:  C P Taylor; N P Bown; A G McGuckin; J Lunec; A J Malcolm; A D Pearson; D Sheer
Journal:  Br J Cancer       Date:  2000-07       Impact factor: 7.640
  10 in total

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