Literature DB >> 9066768

Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. II. Structure elucidation of chloropeptin I.

K Matsuzaki1, T Ogino, T Sunazuka, H Tanaka, S Omura.   

Abstract

The structure of chloropeptin I, a gp120-CD4 binding inhibitor having a potent anti-HIV activity, was elucidated by 1H and 13C NMR experiments and chemical degradation. It is a peptide antibiotic consisting of six aryl amino acids residues and an alpha-oxo aryl acid some of which have chlorine atoms.

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Year:  1997        PMID： 9066768     DOI： 10.7164/antibiotics.50.66

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

1.  Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method.

Authors:  Hiroaki Gouda; Toshiaki Sunazuka; Hideaki Ui; Masaki Handa; Yusuke Sakoh; Yuzuru Iwai; Shuichi Hirono; Satoshi Omura
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-12       Impact factor: 11.205

2.  A Pd(0)-mediated indole (macro)cyclization reaction.

Authors:  Steven P Breazzano; Yam B Poudel; Dale L Boger
Journal:  J Am Chem Soc       Date:  2013-01-17       Impact factor: 15.419

3.  N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.

Authors:  Shibo Jiang; Hong Lu; Shuwen Liu; Qian Zhao; Yuxian He; Asim K Debnath
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

4.  Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.

Authors:  Hiroyuki Shimamura; Steven P Breazzano; Joie Garfunkle; F Scott Kimball; John D Trzupek; Dale L Boger
Journal:  J Am Chem Soc       Date:  2010-06-09       Impact factor: 15.419

5.  Synthesis and stereochemical determination of complestatin A and B (neuroprotectin A and B).

Authors:  Steven P Breazzano; Dale L Boger
Journal:  J Am Chem Soc       Date:  2011-10-20       Impact factor: 15.419

Review 6.  Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.

Authors:  Akinori Okano; Nicholas A Isley; Dale L Boger
Journal:  Chem Rev       Date:  2017-04-24       Impact factor: 60.622

7.  Total synthesis of chloropeptin II (complestatin) and chloropeptin I.

Authors:  Joie Garfunkle; F Scott Kimball; John D Trzupek; Shinobu Takizawa; Hiroyuki Shimamura; Masaki Tomishima; Dale L Boger
Journal:  J Am Chem Soc       Date:  2009-11-11       Impact factor: 15.419

8.  ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation.

Authors:  Hongtao Wang; Zhi Qi; Angi Guo; Qinchao Mao; Hong Lu; Xiuli An; Chenglai Xia; Xiaojuan Li; Asim K Debnath; Shuguang Wu; Shuwen Liu; Shibo Jiang
Journal:  Antimicrob Agents Chemother       Date:  2009-09-28       Impact factor: 5.191

9.  Natural Products from Actinobacteria Associated with Fungus-Growing Termites.

Authors:  René Benndorf; Huijuan Guo; Elisabeth Sommerwerk; Christiane Weigel; Maria Garcia-Altares; Karin Martin; Haofu Hu; Michelle Küfner; Z Wilhelm de Beer; Michael Poulsen; Christine Beemelmanns
Journal:  Antibiotics (Basel)       Date:  2018-09-13
  9 in total

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