| Literature DB >> 9060403 |
A Sabile1, I Poras, D Cherif, P Goodfellow, P Avner.
Abstract
Mouse/human somatic cell hybrids constitute a valuable resource for both genetic and physical mapping. In this report, we describe the production and characterization of a series of six monochromosomal hybrids generated by fusion of murine micro-cells with intact human recipient cells. The presence of each mouse chromosome was characterized by PCR analysis and the integrity of the mouse chromosome retained in the hybrids confirmed by fluorescence in situ hybridization (FISH) analysis.Entities:
Mesh:
Year: 1997 PMID: 9060403 DOI: 10.1007/s003359900362
Source DB: PubMed Journal: Mamm Genome ISSN: 0938-8990 Impact factor: 2.957