| Literature DB >> 9037602 |
G G Bouffard, L M Iyer, J R Idol, V V Braden, A F Cunningham, L A Weintraub, R M Mohr-Tidwell, D C Peluso, R S Fulton, M P Leckie, E D Green.
Abstract
An established goal of the ongoing Human Genome Project is the development and mapping of sequence-tagged sites (STSs) every 100 kb, on average, across all human chromosomes. En route to constructing such a physical map of human chromosome 7, we have generated 1814 chromosome 7-specific STSs. The corresponding PCR assays were designed by the use of DNA sequence determined in our laboratory (79%) or generated elsewhere (21%) and were demonstrated to be suitable for screening yeast artificial chromosome (YAC) libraries. This collection provides the requisite landmarks for constructing a physical map of chromosome 7 at < 100-kb average spacing of STSs.Entities:
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Year: 1997 PMID: 9037602 DOI: 10.1101/gr.7.1.59
Source DB: PubMed Journal: Genome Res ISSN: 1088-9051 Impact factor: 9.043