| Literature DB >> 9032401 |
A Mankertz1, F Persson, J Mankertz, G Blaess, H J Buhk.
Abstract
The origin of DNA replication of porcine circovirus (PCV) was mapped to a 111-bp fragment. On top of a hairpin, a nonanucleotide (TAGTATTAC) homologous to nonanucleotides of other viruses was identified. Mutation of this element abolishes replication. PCV may be related to a virus family characterized by single-stranded circular DNA genomes, rolling-circle replication, and homology of their rep proteins.Entities:
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Year: 1997 PMID: 9032401 PMCID: PMC191374
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103