| Literature DB >> 9029369 |
Y Denizot1, F Dupuis, F Trimoreau, C Verger, A Allegraud, V Praloran.
Abstract
Platelet-activating factor (PAF) is present in human bone marrow leading us to investigate its effect on human bone marrow cell proliferation. While PAF (0.1 microM to 1 nM) stimulates the incorporation of [3H]thymidine by freshly isolated adherent human bone marrow cells, PAF has no effect on non adherent cells. A non-metabolizable PAF agonist is more potent than PAF to stimulate thymidine incorporation in adherent cells. The precise role of PAF in human haematopoiesis in vivo remains to be clarified.Entities:
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Year: 1996 PMID： 9029369 DOI： 10.1016/s0929-7855(96)00447-6
Source DB: PubMed Journal: J Lipid Mediat Cell Signal ISSN： 0929-7855