Literature DB >> 902245

An experimental study of mummification pertinent to the antiquity of cancer.

M R Zimmerman.   

Abstract

The relatively recent description in scientific literature of many types of cancer suggests their infrequency until the relatively recent past, a view supported by the paucity of diagnoses of malignancies in ancient remains. While overall life span was short in antiquity, many individuals did live to the "cancer age," as there is ample evidence of a variety of degenerative disorders. It has been suggested that tumors are not well enough preserved for diagnosis, and tumors experimentally mummified and rehydrated were evaluated as to their preservation. It was found that cancers were actually better preserved than normal tissues. The absence of tumors in ancient tissues must be considered a reflection of a markedly lower incidence than in the modern population of the Lnited States, in which cancer accounts for approximately 17% of all deaths. It is suggested that this increase in cancer is due to factors in the modern industrialized environment.

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Year:  1977        PMID: 902245     DOI: 10.1002/1097-0142(197709)40:3<1358::aid-cncr2820400354>3.0.co;2-j

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  4 in total

Review 1.  Cancer: an old disease, a new disease or something in between?

Authors:  A Rosalie David; Michael R Zimmerman
Journal:  Nat Rev Cancer       Date:  2010-09-03       Impact factor: 60.716

2.  Paleopathological description and diagnosis of metastatic carcinoma in an Early Bronze Age (4588+34 Cal. BP) forager from the Cis-Baikal region of Eastern Siberia.

Authors:  Angela R Lieverse; Daniel H Temple; Vladimir I Bazaliiskii
Journal:  PLoS One       Date:  2014-12-03       Impact factor: 3.240

3.  Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy.

Authors:  Michal Feldman; Israel Hershkovitz; Ella H Sklan; Gila Kahila Bar-Gal; Ildikó Pap; Ildikó Szikossy; Rina Rosin-Arbesfeld
Journal:  PLoS One       Date:  2016-02-10       Impact factor: 3.240

Review 4.  Chemical carcinogens: a review of the science and its associated principles. U.S. Interagency Staff Group on Carcinogens.

Authors: 
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

  4 in total

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