Literature DB >> 9013207

The mechanisms of action of antiprotozoal and anthelmintic drugs in man.

G J Frayha1, J D Smyth, J G Gobert, J Savel.   

Abstract

The mechanisms of action of antiprotozoal and anthelmintic drugs are reviewed according to: (1) drugs interfering with metabolic processes; (2) drugs interfering with reproduction and larval physiology; and (3) drugs interfering with neuromuscular physiology of parasites.

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Year:  1997        PMID： 9013207     DOI： 10.1016/s0306-3623(96)00149-8

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN： 0306-3623


  26 in total

1.  Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure.

Authors:  Robert A Mook; Jiangbo Wang; Xiu-Rong Ren; Minyong Chen; Ivan Spasojevic; Larry S Barak; H Kim Lyerly; Wei Chen
Journal:  Bioorg Med Chem       Date:  2015-08-10       Impact factor: 3.641

2.  Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype.

Authors:  Robert A Mook; Jiangbo Wang; Xiu-Rong Ren; Hailan Piao; H Kim Lyerly; Wei Chen
Journal:  Bioorg Med Chem Lett       Date:  2018-11-12       Impact factor: 2.823

3.  Inhibition of Toxoplasma gondii Growth by Dihydroquinine and Its Mechanisms of Action.

Authors:  Aarin M Huffman; Joseph A Ayariga; Audrey Napier; Boakai K Robertson; Daniel A Abugri
Journal:  Front Cell Infect Microbiol       Date:  2022-05-11       Impact factor: 6.073

4.  Temporal analysis of protozoan lysis in a microfluidic device.

Authors:  Michael F Santillo; Michael L Heien; Andrew G Ewing
Journal:  Lab Chip       Date:  2009-07-03       Impact factor: 6.799

5.  Pentamidine reverses the splicing defects associated with myotonic dystrophy.

Authors:  M Bryan Warf; Masayuki Nakamori; Catherine M Matthys; Charles A Thornton; J Andrew Berglund
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-12       Impact factor: 11.205

6.  Niclosamide inhibits vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia in injured rat carotid arteries.

Authors:  Xiao-Lin Xiao; Nan Hu; Xin-Zi Zhang; Man Jiang; Chang Chen; Rui Ma; Zhen-Gang Ma; Jin-Lai Gao; Xiu-Chen Xuan; Zhi-Jie Sun; De-Li Dong
Journal:  Br J Pharmacol       Date:  2018-04-02       Impact factor: 8.739

7.  Flow cytometry analysis of the effect of allopurinol and the dinitroaniline compound (Chloralin) on the viability and proliferation of Leishmania infantum promastigotes.

Authors:  S W Kamau; R Nunez; F Grimm
Journal:  BMC Pharmacol       Date:  2001-04-05

Review 8.  Progress in Redirecting Antiparasitic Drugs for Cancer Treatment.

Authors:  Haoyang Huang; Qing He; Binghua Guo; Xudong Xu; Yinjuan Wu; Xuerong Li
Journal:  Drug Des Devel Ther       Date:  2021-06-22       Impact factor: 4.162

9.  Altered Gene Expression in the Schistosome-Transmitting Snail Biomphalaria glabrata following Exposure to Niclosamide, the Active Ingredient in the Widely Used Molluscicide Bayluscide.

Authors:  Si-Ming Zhang; Sarah K Buddenborg; Coen M Adema; John T Sullivan; Eric S Loker
Journal:  PLoS Negl Trop Dis       Date:  2015-10-09

10.  Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.

Authors:  Hanlin Tao; Yong Zhang; Xiangang Zeng; Gerald I Shulman; Shengkan Jin
Journal:  Nat Med       Date:  2014-10-05       Impact factor: 53.440
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