Literature DB >> 9008291

Antibody production against hepatitis C virus core and nonstructural 3 proteins is highly sensitive to deficits in T-cell function.

Y Ando1, A Sönnerborg, L Barkholt, A Birkett, B G Ericzon, M Sällberg.   

Abstract

The influence of suppression of CD4+ and CD8+ T cells on the humoral responses to hepatitis C virus (HCV) core and nonstructural 3 proteins was studied. An increasing viral burden cannot substitute for the lack of functional T cells in maintaining humoral HCV-specific responses.

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Year:  1997        PMID： 9008291      PMCID： PMC170485          DOI： 10.1128/cdli.4.1.104-106.1997

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  16 in total

1.  Antibodies against synthetic oligopeptides deduced from the putative core gene for the diagnosis of hepatitis virus infection.

Authors:  H Okamoto; F Tsuda; A Machida; E Munekata; Y Akahane; Y Sugai; K Mashiko; T Mitsui; T Tanaka; Y Miyakawa
Journal:  Hepatology       Date:  1992-02       Impact factor: 17.425

2.  Changes in antibody titers to hepatitis C virus following interferon therapy for chronic infection.

Authors:  A Urushihara; T Sodeyama; A Matsumoto; E Tanaka
Journal:  J Med Virol       Date:  1994-04       Impact factor: 2.327

3.  Expression, isolation, and characterization of the hepatitis C virus ATPase/RNA helicase.

Authors:  L Jin; D L Peterson
Journal:  Arch Biochem Biophys       Date:  1995-10-20       Impact factor: 4.013

4.  Identification of an immunodominant epitope within the capsid protein of hepatitis C virus.

Authors:  M S Nasoff; S L Zebedee; G Inchauspé; A M Prince
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-15       Impact factor: 11.205

5.  Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection.

Authors:  H M Diepolder; R Zachoval; R M Hoffmann; E A Wierenga; T Santantonio; M C Jung; D Eichenlaub; G R Pape
Journal:  Lancet       Date:  1995-10-14       Impact factor: 79.321

6.  Immune response to a single peptide containing an immunodominant region of hepatitis C virus core protein: the isotypes and the recognition site.

Authors:  M Sällberg; U Rudén; B Wahren; L O Magnius
Journal:  Immunol Lett       Date:  1992-06       Impact factor: 3.685

7.  Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus.

Authors:  J Chiba; H Ohba; Y Matsuura; Y Watanabe; T Katayama; S Kikuchi; I Saito; T Miyamura
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

8.  Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C.

Authors:  M Shindo; A M Di Bisceglie; L Cheung; J W Shih; K Cristiano; S M Feinstone; J H Hoofnagle
Journal:  Ann Intern Med       Date:  1991-11-01       Impact factor: 25.391

9.  Levels of hepatitis C virus (HCV) RNA in serum and their relationship to levels of immunoglobulin M and G antibodies against HCV core protein.

Authors:  M Chen; A Sönnerborg; M Sällberg
Journal:  J Clin Microbiol       Date:  1995-03       Impact factor: 5.948

10.  High hepatitis C viraemia and impaired antibody response in patients coinfected with HIV.

Authors:  B Cribier; D Rey; C Schmitt; J M Lang; A Kirn; F Stoll-Keller
Journal:  AIDS       Date:  1995-10       Impact factor: 4.177
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  1 in total

1.  Inhibition of the HCV core protein on the immune response to HBV surface antigen and on HBV gene expression and replication in vivo.

Authors:  Wenbo Zhu; Chunchen Wu; Wanyu Deng; Rongjun Pei; Yun Wang; Liang Cao; Bo Qin; Mengji Lu; Xinwen Chen
Journal:  PLoS One       Date:  2012-09-14       Impact factor: 3.240
  1 in total

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