Literature DB >> 899870

Treatment of advanced breast cancer with chemotherapeutics and inhibition of coagulation and fibrinolysis.

B Astedt, W Mattsson, C Tropé.   

Abstract

A case of advanced breast cancer with cerebral metastasis and pleurisy is reported in which irradiation and cytostatics had failed to retard progressive growth and spread of the tumour. Adjuvant therapy with heparin combined with the fibrinolytic inhibitor tranexamic acid was followed by regression of the cerebral metastasis as well as the pleurisy. When last seen one year later, the patient was free from symptoms.

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Year:  1977        PMID: 899870     DOI: 10.1111/j.0954-6820.1977.tb15735.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  6 in total

1.  Adjuvant treatment of ovarian carcinoma with tranexamic acid.

Authors:  B Astedt
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1980

2.  Effect of tranexamic acid on progress of experimental tumours and on DNA-synthesis.

Authors:  B Astedt; C Tropé
Journal:  Experientia       Date:  1980-06-15

Review 3.  Clinical trials with anticoagulant and antiplatelet therapies.

Authors:  L R Zacharski; K R Meehan; S M Algarra; F A Calvo
Journal:  Cancer Metastasis Rev       Date:  1992-11       Impact factor: 9.264

Review 4.  Venous thromboembolism in cancer patients: an underestimated major health problem.

Authors:  Jihane Khalil; Badr Bensaid; Hanan Elkacemi; Mohamed Afif; Younes Bensaid; Tayeb Kebdani; Noureddine Benjaafar
Journal:  World J Surg Oncol       Date:  2015-06-20       Impact factor: 2.754

5.  Repurposing Tranexamic Acid as an Anticancer Agent.

Authors:  Mary E Law; Bradley J Davis; Amanda F Ghilardi; Elham Yaaghubi; Zaafir M Dulloo; Mengxiong Wang; Olga A Guryanova; Coy D Heldermon; Stephan C Jahn; Ronald K Castellano; Brian K Law
Journal:  Front Pharmacol       Date:  2022-01-13       Impact factor: 5.810

6.  Coupling of proadipocyte growth arrest and differentiation. I. Induction by heparinized medium containing human plasma.

Authors:  B R Krawisz; R E Scott
Journal:  J Cell Biol       Date:  1982-08       Impact factor: 10.539

  6 in total

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