Literature DB >> 7418830

Effect of tranexamic acid on progress of experimental tumours and on DNA-synthesis.

B Astedt, C Tropé.   

Abstract

The fibrinolytic inhibitor tranexamic acid affects certain experimental tumours; it prolongs survival (Lewis lung adenocarcinoma), decreases tumour weight (C3H breast carcinoma), and inhibits ascitic production (AH 130 rat hepatoma). However, it does not significantly influence DNA-synthesis in cell suspensions prepared from the same tumours.

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Year:  1980        PMID： 7418830     DOI： 10.1007/bf01970136

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  20 in total

1.  Coagulative properties of cancers.

Authors:  R A O'MEARA
Journal:  Ir J Med Sci       Date:  1958-10       Impact factor: 1.568

2.  Influence of ovarian hormones on the metabolism of nucleic acids and phospholipids in the rabbit uterus.

Authors:  U BORELL
Journal:  Acta Endocrinol (Copenh)       Date:  1952-02

3.  Effect of proteolytic inhibitors on growth and surface architecture of normal and transformed cells.

Authors:  J G Collard; L A Smets
Journal:  Exp Cell Res       Date:  1974-05       Impact factor: 3.905

4.  Purification and characterization of a cellular fibrinolytic factor associated with oncogenic transformation: the plasminogen activator from SV-40-transformed hamster cells.

Authors:  J K Christman; G Acs
Journal:  Biochim Biophys Acta       Date:  1974-03-27

5.  Formation of the C3-cleaving properdin enzyme on zymosan. Demonstration that factor D is replaceable by proteolytic enzymes.

Authors:  V Brade; A Nicholson; D Bitter-Suermann; U Hadding
Journal:  J Immunol       Date:  1974-12       Impact factor: 5.422

6.  The synthesis of DNA and RNA in normal human endometrium in short-term incubation in vitro and its response to oestradiol and progesterone.

Authors:  S Nordqvist
Journal:  J Endocrinol       Date:  1970-09       Impact factor: 4.286

7.  Plasminogen activator of the blood vessels in tumours and in carrageenin-induced granulomas.

Authors:  C R Pick; D B Cater
Journal:  Br J Exp Pathol       Date:  1971-02

8.  Localization of fibrinolytic activity in uterine cancer.

Authors:  G Weiss; F K Beller
Journal:  Am J Obstet Gynecol       Date:  1969-04-01       Impact factor: 8.661

9.  Fibrinolysis and antifibrinolytic drugs in the growth and spread of tumours.

Authors:  H Peterson
Journal:  Cancer Treat Rev       Date:  1977-09       Impact factor: 12.111

10.  The conversion of C'IS to C'1 esterase by plasmin and trypsin.

Authors:  O D Ratnoff; G B Naff
Journal:  J Exp Med       Date:  1967-02-01       Impact factor: 14.307
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  1 in total

1.  Repurposing Tranexamic Acid as an Anticancer Agent.

Authors:  Mary E Law; Bradley J Davis; Amanda F Ghilardi; Elham Yaaghubi; Zaafir M Dulloo; Mengxiong Wang; Olga A Guryanova; Coy D Heldermon; Stephan C Jahn; Ronald K Castellano; Brian K Law
Journal:  Front Pharmacol       Date:  2022-01-13       Impact factor: 5.810
  1 in total

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