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Literature DB >> 8994822

Mitosis: don't get mad, get even.

Abstract

The 'mitotic spindle checkpoint' ensures that, before a cell exits from mitosis, all of its chromosomes are aligned on the spindle to form the metaphase plate. Mad2 is an essential component of this checkpoint system and it binds specifically to unattached kinetochores.

Entities: Gene

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Year: 1996 PMID： 8994822 DOI： 10.1016/s0960-9822(02)70781-1

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

6 in total

1. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1.

Authors: C M Pfleger; A Salic; E Lee; M W Kirschner
Journal: Genes Dev Date: 2001-07-15 Impact factor: 11.361

2. Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin.

Authors: Li Wang; Fang Yin; Yulei Du; Bei Chen; Shuhui Liang; Yongguo Zhang; Wenqi Du; Kaichun Wu; Jie Ding; Daiming Fan
Journal: Tumour Biol Date: 2010-05-04

Mitosis: don't get mad, get even.

1. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1.

2. Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin.

3. A Failsafe for Sensing Chromatid Tension in Mitosis with the Histone H3 Tail in Saccharomyces cerevisiae.

4. LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.

5. C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle.

6. Analysis of the role of GSK3 in the mitotic checkpoint.