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Literature DB >> 8988600

Antiplatelet arylnaphthalide lignans from Justicia procumbens.

C C Chen¹, W C Hsin, F N Ko, Y L Huang, J C Ou, C M Teng.

Abstract

Fractionation of the EtOH extract of Justicia procumbens, guided by antiplatelet bioassay, led to the isolation of nine known arylnaphthalide lignans, neojusticin A (1), justicidin B (2), justicidin A (3), taiwanin E methyl ether (4), neojusticin B (5), chinensinaphthol methyl ether (6), taiwanin E (8), chinensinaphthol (9), and diphyllin (10), and a new arylnaphthalide lignan that was characterized by spectral means as 4'-demethylchinensinaphthol methyl ether (7). Compounds 1, 2, 4, and 8 significantly inhibited platelet aggregation.

Entities: Chemical Disease Species

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Year: 1996 PMID： 8988600 DOI： 10.1021/np960443+

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

11 in total

1. Synthesis of 2,3-disubstituted benzo[b]furans by the palladium-catalyzed coupling of o-iodoanisoles and terminal alkynes, followed by electrophilic cyclization.

Authors: Dawei Yue; Tuanli Yao; Richard C Larock
Journal: J Org Chem Date: 2005-12-09 Impact factor: 4.354

2. Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.

Authors: John L Woodard; Andrew C Huntsman; Pratiq A Patel; Hee-Byung Chai; Ragu Kanagasabai; Soumendrakrishna Karmahapatra; Alexandria N Young; Yulin Ren; Malcolm S Cole; Denisse Herrera; Jack C Yalowich; A Douglas Kinghorn; Joanna E Burdette; James R Fuchs
Journal: Bioorg Med Chem Date: 2018-03-23 Impact factor: 3.641

Review 3. Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery.

Authors: Chuang Zhao; K P Rakesh; Saira Mumtaz; Balakrishna Moku; Abdullah M Asiri; Hadi M Marwani; H M Manukumar; Hua-Li Qin
Journal: RSC Adv Date: 2018-03-06 Impact factor: 4.036

4. Evaluation and structure-activity relationship analysis of a new series of arylnaphthalene lignans as potential anti-tumor agents.

Authors: Jiaoyang Luo; Yichen Hu; Weijun Kong; Meihua Yang
Journal: PLoS One Date: 2014-03-27 Impact factor: 3.240

5. Preparative isolation and purification of lignans from Justicia procumbens using high-speed counter-current chromatography in stepwise elution mode.

Authors: Peijuan Zhou; Qijun Luo; Lijian Ding; Fang Fang; Ye Yuan; Juanjuan Chen; Jinrong Zhang; Haixiao Jin; Shan He
Journal: Molecules Date: 2015-04-20 Impact factor: 4.411

6. A Strategy for Preparative Separation of 10 Lignans from Justicia procumbens L. by High-Speed Counter-Current Chromatography.

Authors: Jiaojiao Jiang; Hongjing Dong; Tao Wang; Ruixuan Zhao; Yan Mu; Yanling Geng; Zhenjia Zheng; Xiao Wang
Journal: Molecules Date: 2017-11-23 Impact factor: 4.411

7. A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees.

Authors: Songtao Wu; Yanfang Yang; Bo Liu; Zhoutao Xie; Weichen Xiong; Pengfei Hao; Wenping Xiao; Yuan Sun; Zhongzhu Ai; Hezhen Wu
Journal: J Enzyme Inhib Med Chem Date: 2019-12 Impact factor: 5.051