Literature DB >> 8988599

New triterpenoid saponins from Gynostemma pentaphyllum.

L Hu1, Z Chen, Y Xie.   

Abstract

Three new triterpenoidal saponins (1-3), together with the known compound 4, were isolated from a MeOH extract of the aerial parts of Gynostemma pentaphyllum. Their structures were elucidated on the basis of chemical and spectral methods, such as 1H-1H DQFCOSY, HMQC, HMBC, and TOCSY NMR spectra. The aglycon moiety of 1 and 2 is a new dammarane-type triterpene 12-oxo-2 alpha, 3 beta, 20 (S)-trihydroxydammar- 24-ene.

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Year:  1996        PMID: 8988599     DOI: 10.1021/np960445u

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

1.  Transcriptome profiling and insilico analysis of Gynostemma pentaphyllum using a next generation sequencer.

Authors:  Sathiyamoorthy Subramaniyam; Ramya Mathiyalagan; In Jun Gyo; Lee Bum-Soo; Lee Sungyoung; Yang Deok Chun
Journal:  Plant Cell Rep       Date:  2011-07-19       Impact factor: 4.570

2.  Production of dammarenediol-II triterpene in a cell suspension culture of transgenic tobacco.

Authors:  Jung-Yeon Han; Hong-Yan Wang; Yong-Eui Choi
Journal:  Plant Cell Rep       Date:  2013-10-20       Impact factor: 4.570

3.  The triterpenoid sapogenin (2α-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling.

Authors:  Zhifu Xie; Haowen Jiang; Wei Liu; Xinwen Zhang; Dakai Chen; Shuimei Sun; Chendong Zhou; Jia Liu; Sheng Bao; Xiachang Wang; Yinan Zhang; Jia Li; Lihong Hu; Jingya Li
Journal:  Cell Death Dis       Date:  2020-09-17       Impact factor: 8.469

4.  Gynostemma pentaphyllum polysaccharides ameliorate non-alcoholic steatohepatitis in mice associated with gut microbiota and the TLR2/NLRP3 pathway.

Authors:  Si-Ran Yue; Yi-Yun Tan; Lei Zhang; Bao-Jun Zhang; Feng-Yan Jiang; Guang Ji; Bao-Cheng Liu; Rui-Rui Wang
Journal:  Front Endocrinol (Lausanne)       Date:  2022-07-22       Impact factor: 6.055

5.  Gypenosides induce cell death and alter gene expression in human oral cancer HSC-3 cells.

Authors:  Kung-Wen Lu; Yi-Shih Ma; Fu-Shun Yu; Yi-Ping Huang; Yung-Lin Chu; Rick Sai-Chuen Wu; Ching-Lung Liao; Fu-Shin Chueh; Jing-Gung Chung
Journal:  Exp Ther Med       Date:  2017-07-25       Impact factor: 2.447

  5 in total

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