Literature DB >> 8988195

Elastography of breast lesions: initial clinical results.

B S Garra1, E I Cespedes, J Ophir, S R Spratt, R A Zuurbier, C M Magnant, M F Pennanen.   

Abstract

PURPOSE: To determine the appearance of various breast lesions on elastograms and to explore the potential of elastography in the diagnosis of breast lesions.
MATERIALS AND METHODS: A total of 46 breast lesions were examined with elastography. Patients underwent biopsy or aspiration of all lesions, revealing 15 fibroadenomas, 12 carcinomas, six fibrocystic nodules, and 13 other lesions. The elastogram was generated from radio-frequency data collected with use of a 5-MHz linear-array transducer. The elastogram and corresponding sonogram were evaluated by a single observer for lesion visualization, relative brightness, and margin definition and regularity. The sizes of the lesions at each imaging examination and at biopsy were recorded and compared.
RESULTS: Softer tissues such as fat appear as bright areas on elastograms. Firm tissues, including parenchyma, cancers, and other masses, appear darker. The cancers were statistically significantly darker than fibroadenomas (P < .005) and substantially larger on the elastogram than on the sonogram. Seventy-three percent of fibroadenomas and 56% of solid benign lesions could be distinguished from cancers by using lesion brightness and size difference. Some cancers that appeared as areas of shadowing on sonograms appeared as discrete masses on elastograms.
CONCLUSION: Elastography has the potential to be useful in the evaluation of areas of shadowing on the sonogram. It also may be helpful in the distinction of benign from malignant masses.

Entities:  

Mesh:

Year:  1997        PMID: 8988195     DOI: 10.1148/radiology.202.1.8988195

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  169 in total

1.  Linear and nonlinear elastic modulus imaging: an application to breast cancer diagnosis.

Authors:  Sevan Goenezen; Jean-Francois Dord; Zac Sink; Paul E Barbone; Jingfeng Jiang; Timothy J Hall; Assad A Oberai
Journal:  IEEE Trans Med Imaging       Date:  2012-05-30       Impact factor: 10.048

2.  Sonoelastography findings of biceps tendinitis and tendinosis.

Authors:  Joong-Bae Seo; Jae-Sung Yoo; Jee-Won Ryu
Journal:  J Ultrasound       Date:  2014-03-13

3.  A pilot study to evaluate assisted freehand ultrasound elasticity imaging in the sizing of early breast cancer: a comparison of B-mode and AFUSON elasticity ultrasound with histopathology measurements.

Authors:  R E English; J Li; A J C Parker; D Roskell; R F Adams; V Parulekar; J Baldwin; Y Chi; J A Noble
Journal:  Br J Radiol       Date:  2011-06-01       Impact factor: 3.039

4.  Harmonic Motion Imaging (HMI) for Tumor Imaging and Treatment Monitoring.

Authors:  Elisa E Konofagou; Caroline Maleke; Jonathan Vappou
Journal:  Curr Med Imaging Rev       Date:  2012

5.  Linear approach to axial resolution in elasticity imaging.

Authors:  Jie Liu; Craig K Abbey; Michael F Insana
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2004-06       Impact factor: 2.725

6.  Analysis of shear strain imaging for classifying breast masses: finite element and phantom results.

Authors:  Haiyan Xu; Tomy Varghese; Ernest L Madsen
Journal:  Med Phys       Date:  2011-11       Impact factor: 4.071

7.  Real-time sono-elastography in the diagnosis of diffuse liver diseases.

Authors:  Dan Ionuţ Gheonea; Adrian Săftoiu; Tudorel Ciurea; Florin Gorunescu; Sevastiţa Iordache; Gabriel Lucian Popescu; Smaranda Belciug; Marina Gorunescu; Larisa Săndulescu
Journal:  World J Gastroenterol       Date:  2010-04-14       Impact factor: 5.742

Review 8.  Elastography: modality-specific approaches, clinical applications, and research horizons.

Authors:  Yufei Li; Jess G Snedeker
Journal:  Skeletal Radiol       Date:  2010-03-30       Impact factor: 2.199

9.  Volumetric elasticity imaging with a 2-D CMUT array.

Authors:  Ted G Fisher; Timothy J Hall; Satchi Panda; Michael S Richards; Paul E Barbone; Jingfeng Jiang; Jeff Resnick; Steve Barnes
Journal:  Ultrasound Med Biol       Date:  2010-06       Impact factor: 2.998

10.  pH-induced contrast in viscoelasticity imaging of biopolymers.

Authors:  R D Yapp; M F Insana
Journal:  Phys Med Biol       Date:  2009-01-27       Impact factor: 3.609

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