Reassignment of MYCL1 to human chromosome 1p34.3 by fluorescence in situ hybridization.

MYCL1 has been previously mapped to 1p32. This position was in contradiction with our mapping data of 1p deletions in neuroblastoma cell lines. Using FISH on high resolution R-banded chromosomes with a YAC clone for MYCL1 we were able to reassign the gene to subband 1p34.3. This new map position is of importance for the establishment of an integrated map for chromosome 1 and the search for disease genes in this region.