| Literature DB >> 897669 |
Abstract
The use of 8-methoxypsoralen for treating psoriasis could prove hazardous if this photosensitizing agent enters the ocular lens. Phosphorescence spectra of intact rat lenses reveal concentrations of 8-methoxypsoralen on the order 10(-5)M after intraperitoneal injection of 8-methoxypsoralen. There is evidence that this drug can function as a photosensitizing agent, enhancing ultraviolet-induced changes within the lens.Entities:
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Year: 1977 PMID: 897669 DOI: 10.1126/science.897669
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728