[Lysosomes and lysosomal enzymes in the wall of imbalanced arteries of rats (author's transl)].

The electron microscope demonstration of reaction products of the acid phosphatase within matrix vesicles (=extracellular membrane-bound corpuscles) of the wall of hemodynamic or metabolic imbalanced arteries stimulated experiments about the activities of lysosomal enzymes in the wall of wrongly loaded arteries. In our case arteries without any hemodynamic function (="null function") were investigated 4, 5, 7, 13 and 14 days after applying a ligature. In relation to the nonligated testicular arteries of the other side the wall of theligated vessels show an increase of lysosomal glycosidases (beta-N-Acetyl-glucosaminidase and beta-galactosidase) about 40-70%. The significance of the extracellular lysosomes for transformations of the vessel wall under physiological and pathological conditions is discussed.