Literature DB >> 8970711

Female-controlled methods to prevent sexual transmission of HIV.

C J Elias1, C Coggins.   

Abstract

UNLABELLED: THE NEED FOR PREVENTION: Women throughout the world face a growing risk of infection with HIV. Consistent condom use, one cornerstone of primary prevention strategy, is not always feasible for many women. Consequently, women urgently need infection prevention technology that is within their personal control.
METHODS: This session will review current efforts to develop and test female-controlled methods for preventing sexual transmission of HIV and other sexually transmitted pathogens. Both physical and chemical methods will be summarized, including recent findings concerning the efficacy and acceptability of the vaginal pouch (female condom), as well as an overview of research on vaginal microbicides. Data from studies of existing over-the-counter spermicides will be reviewed. The wide range of novel microbicidal products currently being evaluated in the laboratory and early clinical trials demonstrate the breadth of possibilities presented by chemical barrier methods. However, formidible challenges face public and private sector research and development efforts. This session will conclude by highlighting several issues related to the clinical evaluation and introduction of female-controlled prevention technology.

Entities:  

Keywords:  Americas; Barrier Methods; Clinical Research; Clinical Trials; Contraception; Contraceptive Agents; Contraceptive Methods; Developed Countries; Diseases; Economic Factors; Family Planning; Hiv Infections--prevention and control; Infections; Literature Review; North America; Northern America; Reproductive Tract Infections; Research And Development; Research Methodology; Sexually Transmitted Diseases--prevention and control; Spermicidal Contraceptive Agents; Technology; United States; Viral Diseases

Mesh:

Substances:

Year:  1996        PMID: 8970711

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  35 in total

1.  Effect of an STD/HIV behavioral intervention on women's use of the female condom.

Authors:  Nancy Van Devanter; Virginia Gonzales; Cheryl Merzel; Nina S Parikh; David Celantano; Judith Greenberg
Journal:  Am J Public Health       Date:  2002-01       Impact factor: 9.308

2.  In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides.

Authors:  Youssef Gali; Olivier Delezay; Joachim Brouwers; Noura Addad; Patrick Augustijns; Thomas Bourlet; Hind Hamzeh-Cognasse; Kevin K Ariën; Bruno Pozzetto; Guido Vanham
Journal:  Antimicrob Agents Chemother       Date:  2010-10-04       Impact factor: 5.191

3.  Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention.

Authors:  Lin Wang; Alexandra Beumer Sassi; Dorothy Patton; Charles Isaacs; B J Moncla; Phalguni Gupta; Lisa Cencia Rohan
Journal:  Drug Dev Ind Pharm       Date:  2011-12-10       Impact factor: 3.225

4.  Protection of mice from a Chlamydia trachomatis vaginal infection using a Salicylidene acylhydrazide, a potential microbicide.

Authors:  Anatoly Slepenkin; Hencelyn Chu; Mikael Elofsson; Pia Keyser; Ellena M Peterson
Journal:  J Infect Dis       Date:  2011-09-20       Impact factor: 5.226

5.  Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides.

Authors:  P Greenhead; P Hayes; P S Watts; K G Laing; G E Griffin; R J Shattock
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

Review 6.  Ethical challenges in efficacy trials of vaginal microbicides for HIV prevention.

Authors:  I de Zoysa; C J Elias; M E Bentley
Journal:  Am J Public Health       Date:  1998-04       Impact factor: 9.308

7.  An evaluation of methods to improve the reporting of adherence in a placebo gel trial in Andhra Pradesh, India.

Authors:  Sharon A Abbott; Barbara A Friedland; Avina Sarna; Lauren L Katzen; Ulrike Rawiel; Aylur K Srikrishnan; C S Shalini; Waimar Tun; Christine A Kelly; Suniti Solomon; Barbara S Mensch
Journal:  AIDS Behav       Date:  2013-07

8.  Measuring self-efficacy to use vaginal microbicides: the Microbicide Use Self-Efficacy instrument.

Authors:  Joseph L Fava; Jacob J van den Berg; Rochelle K Rosen; Liz Salomon; Sara Vargas; Anna L Christensen; Megan Pinkston; Kathleen M Morrow
Journal:  Sex Health       Date:  2013-08       Impact factor: 2.706

9.  In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission.

Authors:  Charlene S Dezzutti; V Nicole James; Artur Ramos; Sharon T Sullivan; Aladin Siddig; Timothy J Bush; Lisa A Grohskopf; Lynn Paxton; Shambavi Subbarao; Clyde E Hart
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

10.  PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture.

Authors:  Humberto H Lara; Liliana Ixtepan-Turrent; Elsa N Garza-Treviño; Cristina Rodriguez-Padilla
Journal:  J Nanobiotechnology       Date:  2010-07-13       Impact factor: 10.435

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