Literature DB >> 8970017

Parameter identifiability is required in pooled data methods.

J A Jacquez1.   

Abstract

In pooled data methods such as naive pooled data methods and NONMEM, the number of sample points per individual may be less than the number of unknown parameters so that the values of the parameters are not estimable in individuals. However, for the moments of the distributions of the parameters to be estimable, the basic parameters must be identifiable.

Mesh:

Year:  1996        PMID: 8970017     DOI: 10.1007/bf02353673

Source DB:  PubMed          Journal:  J Pharmacokinet Biopharm        ISSN: 0090-466X


  3 in total

1.  Estimation of population characteristics of pharmacokinetic parameters from routine clinical data.

Authors:  L B Sheiner; B Rosenberg; V V Marathe
Journal:  J Pharmacokinet Biopharm       Date:  1977-10

2.  Parameter estimation: local identifiability of parameters.

Authors:  J A Jacquez; T Perry
Journal:  Am J Physiol       Date:  1990-04

3.  Identifiability: the first step in parameter estimation.

Authors:  J A Jacquez
Journal:  Fed Proc       Date:  1987-06
  3 in total
  3 in total

1.  Population pharmacokinetic modeling of plasma Δ9-tetrahydrocannabinol and an active and inactive metabolite following controlled smoked cannabis administration.

Authors:  Cristina Sempio; Marilyn A Huestis; Susan K Mikulich-Gilbertson; Jost Klawitter; Uwe Christians; Thomas K Henthorn
Journal:  Br J Clin Pharmacol       Date:  2020-01-20       Impact factor: 4.335

Review 2.  Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations.

Authors:  Cornelia B Landersdorfer; Jürgen B Bulitta; Martina Kinzig; Ulrike Holzgrabe; Fritz Sörgel
Journal:  Clin Pharmacokinet       Date:  2009       Impact factor: 6.447

3.  Population pharmacokinetic modelling for enterohepatic circulation of mycophenolic acid in healthy Chinese and the influence of polymorphisms in UGT1A9.

Authors:  Zheng Jiao; Jun-Jie Ding; Jie Shen; Hui-Qi Liang; Long-Jin Zhong; Yi Wang; Ming-Kang Zhong; Wei-Yue Lu
Journal:  Br J Clin Pharmacol       Date:  2008-02-15       Impact factor: 4.335

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.