Literature DB >> 896465

An ethidium-induced double helix of poly(dA)-poly(rU).

E A Lehrman, D M Crothers.   

Abstract

Equilibrium dialysis, relaxation kinetic, melting, and continuous variation mixing experiments on complexes of poly(dA) and poly(rU) demonstrate that ethidium induces conversion of a 1:1 mixture of these homopolymers (at one molar salt and 19 degrees C) from a three stranded to a two stranded helix. This is the first demonstration of a double helix of poly(dA)-poly(rU) in solution.

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Year:  1977        PMID： 896465      PMCID： PMC343762          DOI： 10.1093/nar/4.5.1381

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  10 in total

1.  DNA-ethidium reaction kinetics: demonstration of direct ligand transfer between DNA binding sites.

Authors:  J L Bresloff; D M Crothers
Journal:  J Mol Biol       Date:  1975-06-15       Impact factor: 5.469

2.  MULTISTRANDED DNA HOMOPOLYMER INTERACTIONS.

Authors:  R B INMAN
Journal:  J Mol Biol       Date:  1964-10       Impact factor: 5.469

3.  Kinetics of ethidium bromide binding as a probe of transfer ribonucleic acid structure.

Authors:  T R Tritton; S C Mohr
Journal:  Biochemistry       Date:  1973-02-27       Impact factor: 3.162

4.  [Interaction of ethidium hydrobromate (EH) with polyribonucleotides. Applications to the study of hybridization reactions].

Authors:  J B Le Pecq; C Paoletti
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1965-06-28

5.  Statistical thermodynamics of nucleic acid melting transitions with coupled binding equilibria.

Authors:  D M Crothers
Journal:  Biopolymers       Date:  1971-11       Impact factor: 2.505

6.  Calculation of binding isotherms for heterogenous polymers.

Authors:  D M Crothers
Journal:  Biopolymers       Date:  1968-04       Impact factor: 2.505

7.  Heats of the helix-coil transitions of the poly A-poly U complexes.

Authors:  H Krakauer; J M Sturtevant
Journal:  Biopolymers       Date:  1968-04       Impact factor: 2.505

8.  Ethidium bromide as a cooperative effector of a DNA structure.

Authors:  F M Pohl; T M Jovin; W Baehr; J J Holbrook
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

9.  Stablilzation of two-standard ribohomopolymer helices and destabilzation of a three-stranded helix by ethidium bromide.

Authors:  M J Waring
Journal:  Biochem J       Date:  1974-11       Impact factor: 3.857

10.  Physical and chemical characterization of two- and three-stranded adenine-thymine and adenine-uracil homopolymer complexes.

Authors:  M Riley; B Maling
Journal:  J Mol Biol       Date:  1966-09       Impact factor: 5.469
  10 in total
  7 in total

1.  Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.

Authors:  Y W Park; K J Breslauer
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-15       Impact factor: 11.205

2.  Probing the molecular recognition of a DNA.RNA hybrid duplex.

Authors:  Richard T Wheelhouse; Nichola C Garbett; Niklaas J Buurma; Jonathan B Chaires
Journal:  Angew Chem Int Ed Engl       Date:  2010-04-19       Impact factor: 15.336

3.  Complete disproportionation of duplex poly(dT)*poly(dA) into triplex poly(dT)*poly(dA)*poly(dT) and poly(dA) by coralyne.

Authors:  Matjaz Polak; Nicholas V Hud
Journal:  Nucleic Acids Res       Date:  2002-02-15       Impact factor: 16.971

4.  Intercalation of ethidium bromide into a triple-stranded oligonucleotide.

Authors:  J L Mergny; D Collier; M Rougée; T Montenay-Garestier; C Hélène
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

5.  Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by intercalating dyes.

Authors:  N K Tanner; T R Cech
Journal:  Nucleic Acids Res       Date:  1985-11-11       Impact factor: 16.971

6.  Binding properties of Ru(II) polypyridyl complexes with poly(U)·poly(A)*poly(U) triplex: the ancillary ligand effect on third-strand stabilization.

Authors:  Li-Feng Tan; Ling-Jun Xie; Xiao-Nan Sun
Journal:  J Biol Inorg Chem       Date:  2012-10-31       Impact factor: 3.358

7.  Ligand-induced formation of nucleic acid triple helices.

Authors:  D S Pilch; K J Breslauer
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-27       Impact factor: 11.205
  7 in total

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