Literature DB >> 8960033

Positive economic and diagnostic accuracy impacts of on-site evaluation of fine needle aspiration biopsies by pathologists.

H A Saleh1, G Khatib.   

Abstract

OBJECTIVE: To investigate the impact of pathologists' immediate evaluation of fine needle aspiration biopsy (FNAB) on increasing diagnostic yield and decreasing related expenses. STUDY
DESIGN: All FNABs performed at our 420-bed hospital between January 1992 and December 1994 were reviewed. The 1992-1993 FNABs were all performed without pathologist attendance. Smears were wet fixed in 95% alcohol and later stained by the Papanicolaou or hematoxylin and eosin methods. The remaining aspirated material was collected in Saccomano's preservative, and a cell block was made. Nearly all the 1994 FNABs were performed with the pathologist present; he examined air-dried, Diff-Quik-stained smears for preliminary evaluation of the aspirate. An average of three passes were done. The rest of the procedure was as usual.
RESULTS: The total number of 1992-1993 FNABs was 227 (108 + 119); of them, 104 (46%) were inadequate for diagnosis. In contrast, the 1994 FNABs totaled 169, with only 40 (24%) inadequate for diagnosis. The vast majority of the aspirates were done on deep-seated lesions under computed tomography (CT) guidance.
CONCLUSION: The results of our experience indicate that on-site evaluation by a pathologist greatly increases the diagnostic yield. Another advantage is the significant financial savings as compared to excisional tissue biopsy. In general, the expenses of a CT-guided FNAB (e.g., pancreas) average around $1,400, while charges for excisional biopsy under general anesthesia with a subsequent two- to three-day hospitalization average about $7,720.

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Year:  1996        PMID: 8960033     DOI: 10.1159/000333985

Source DB:  PubMed          Journal:  Acta Cytol        ISSN: 0001-5547            Impact factor:   2.319


  8 in total

1.  Improved FNA cytology results with a near patient diagnosis service for non-breast lesions.

Authors:  F Mayall; A Denford; B Chang; A Darlington
Journal:  J Clin Pathol       Date:  1998-07       Impact factor: 3.411

Review 2.  Rapid on-site evaluation increases endoscopic ultrasound-guided fine-needle aspiration adequacy for pancreatic lesions.

Authors:  Robert L Schmidt; Benjamin L Witt; Anna P Matynia; Gonzalo Barraza; Lester J Layfield; Douglas G Adler
Journal:  Dig Dis Sci       Date:  2012-10-04       Impact factor: 3.199

3.  Methionyl-tRNA synthetase and aminoacyl-tRNA synthetases interacting multi-functional protein-lacking exon 2 as potential diagnostic biomarkers for lung cancer.

Authors:  Taehee Kim; Kyosun Lee; Ji Hae Nahm; Eun Young Kim; Sang Hoon Lee; Yoon Soo Chang
Journal:  Am J Cancer Res       Date:  2021-06-15       Impact factor: 6.166

4.  Efficacy of rapid on-site evaluation for diagnosing pulmonary lesions and mediastinal lymph nodes: a systematic review and meta-analysis.

Authors:  Xi Chen; Bing Wan; Yangyang Xu; Yong Song; Ping Zhan; Litang Huang; Hongbing Liu; Dang Lin; Tangfeng Lv
Journal:  Transl Lung Cancer Res       Date:  2019-12

5.  Fast drying of Fine Needle Aspiration slides using a hand held fan: impact on turn around time and staining quality.

Authors:  Mirza A Baig; Lamia Fathallah; Jining Feng; Mujtaba Husain; David G Grignon; Mousa A Al-Abbadi
Journal:  Cytojournal       Date:  2006-04-19       Impact factor: 2.091

6.  Liver metastases of pancreatic acinar cell carcinoma with marked nuclear atypia and pleomorphism diagnosed by EUS FNA cytology: a case report with emphasis on FNA cytological findings.

Authors:  Hong Q Peng; Peter Darwin; John C Papadimitriou; Cinthia B Drachenberg
Journal:  Cytojournal       Date:  2006-12-30       Impact factor: 2.091

7.  Comparison of 1869 thyroid ultrasound-guided fine-needle aspiration biopsies between general surgeons and interventional radiologists.

Authors:  Hilmi Bozkurt; Oktay İrkörücü; Mehmet Aziret; Enver Reyhan; Mehmet Kemal Okuyan
Journal:  Ann Med Surg (Lond)       Date:  2016-08-02

8.  Inadequate fine needle aspiration biopsy samples: pathologists versus other specialists.

Authors:  G S Gomez-Macías; R Garza-Guajardo; J Segura-Luna; O Barboza-Quintana
Journal:  Cytojournal       Date:  2009-06-18       Impact factor: 2.091

  8 in total

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