Literature DB >> 23053888

Rapid on-site evaluation increases endoscopic ultrasound-guided fine-needle aspiration adequacy for pancreatic lesions.

Robert L Schmidt1, Benjamin L Witt, Anna P Matynia, Gonzalo Barraza, Lester J Layfield, Douglas G Adler.   

Abstract

BACKGROUND: Rapid on-site evaluation (ROSE) has the potential to improve adequacy rates and affect other outcomes; however, there have been few comparative studies to assess the impact of ROSE in the setting of ultrasound-guided endoscopic fine-needle aspiration cytology for pancreatic lesions. AIMS: To determine whether ROSE improves adequacy rates of endoscopic fine-needle aspiration cytology for pancreatic lesions.
METHODS: Systematic review and meta-analysis of studies reporting a head-to-head comparison of adequacy or diagnostic accuracy (with ROSE vs. without ROSE) at a single site.
RESULTS: ROSE was associated with a statistically significant (p < 0.001) improvement in the adequacy rate (average 10 %, 95 % CI: 5-24 %). The impact of ROSE depends on the per-pass adequacy rate without ROSE. ROSE had no impact on diagnostic yield (p < 0.76).
CONCLUSIONS: ROSE is associated with an improvement in adequacy rates when implemented at sites where the per-case adequacy rate without ROSE is low (<90 %). It is unclear whether the type of assessor (pathologist vs. non-pathologist) has a significant impact on the success rate of ROSE. ROSE has no impact on diagnostic yield. Studies should employ head-to-head comparisons of cohorts with and without ROSE at a single location.

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Year:  2012        PMID: 23053888     DOI: 10.1007/s10620-012-2411-1

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


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Authors:  K Drak Alsibai; B Denis; J Bottlaender; I Kleinclaus; P Straub; M Fabre
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Authors:  Robert L Schmidt; Douglas G Adler
Journal:  Am J Gastroenterol       Date:  2012-09       Impact factor: 10.864

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6.  Influence of on-site cytopathology evaluation on the diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of solid pancreatic masses.

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2.  Rapid on-site evaluation reduces needle passes in endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic lesions: a risk-benefit analysis.

Authors:  Robert L Schmidt; Brandon S Walker; Kirsten Howard; Lester J Layfield; Douglas G Adler
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5.  This 'Rose' Has no Thorns-Diagnostic Utility of 'Rapid On-Site Evaluation' (ROSE) in Fine Needle Aspiration Cytology.

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6.  Telecytology for Rapid On-Site Evaluation: Current Status.

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7.  The presence of rapid on-site evaluation did not increase the adequacy and diagnostic accuracy of endoscopic ultrasound-guided tissue acquisition of solid pancreatic lesions with core needle.

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8.  The clinical impact of immediate on-site cytopathology evaluation during endoscopic ultrasound-guided fine needle aspiration of pancreatic masses: a prospective multicenter randomized controlled trial.

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9.  Protein Signatures and Tissue Diagnosis of Pancreatic Cancer.

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10.  When Is Rapid On-Site Evaluation Cost-Effective for Fine-Needle Aspiration Biopsy?

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