Literature DB >> 894203

A simplified micromethod for the determination of the acetylator phenotype.

J J Hoo, L Hussein, H W Goedde.   

Abstract

A simplified and rapid method is described for phenotyping of sulfamethazine acetylation. Two hours after a test dose of sulfamethazine, free and total sulfamethazine are estimated in blood drawn either by capillary or venipuncture. The present method offers sharp segregation between slow and rapid acetylators, requires micro blood volumes drawn from finger- or ear pucture, and is more convenient for population genetics survey as well as for clinical investigations.

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Year:  1977        PMID: 894203     DOI: 10.1515/cclm.1977.15.1-12.329

Source DB:  PubMed          Journal:  J Clin Chem Clin Biochem        ISSN: 0340-076X


  3 in total

1.  Glucose-6-phosphate dehydrogenase deficiency and sulfadimidin acetylation phenotypes in Egyptian oases.

Authors:  L Hussein; G Yamamah; A Saleh
Journal:  Biochem Genet       Date:  1992-04       Impact factor: 1.890

2.  Ecogenetic studies in Atacameño Indians.

Authors:  H W Goedde; F Rothhammer; H G Benkmann; P Bogdanski
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

3.  Human acetylator polymorphism: estimate of allele frequency in Libya and details of global distribution.

Authors:  A K Karim; M S Elfellah; D A Evans
Journal:  J Med Genet       Date:  1981-10       Impact factor: 6.318

  3 in total

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