PURPOSE: To use MR imaging in the analysis of the size of the normal pineal gland in infants, children, and adolescents. METHODS: We retrospectively analyzed the size of the pineal gland in 249 patients (129 male and 120 female) aged 2 weeks to 20 years old. The maximum length (L), height (H), and width (W) of the gland were determined from a combination of sagittal, coronal, and axial MR images obtained on a 1.5-T scanner. The volume was calculated by using the formula 1/2 x L x H x W. RESULTS: The size of the pineal gland was significantly smaller in patients younger than 2 years old than in older patients. The size of the pineal gland increased until 2 years of age and remained stationary between the ages of 2 and 20 years. We found a large variation in size among all age groups. No difference in size was noted between males and females. CONCLUSION: This study establishes norms for pineal gland size in infants younger than 2 years old and in children and adolescents 2 to 20 years old as detected with MR imaging. Knowledge of the size of the normal pineal gland is important in the detection of abnormalities of the pineal gland, particularly neoplasms.
PURPOSE: To use MR imaging in the analysis of the size of the normal pineal gland in infants, children, and adolescents. METHODS: We retrospectively analyzed the size of the pineal gland in 249 patients (129 male and 120 female) aged 2 weeks to 20 years old. The maximum length (L), height (H), and width (W) of the gland were determined from a combination of sagittal, coronal, and axial MR images obtained on a 1.5-T scanner. The volume was calculated by using the formula 1/2 x L x H x W. RESULTS: The size of the pineal gland was significantly smaller in patients younger than 2 years old than in older patients. The size of the pineal gland increased until 2 years of age and remained stationary between the ages of 2 and 20 years. We found a large variation in size among all age groups. No difference in size was noted between males and females. CONCLUSION: This study establishes norms for pineal gland size in infants younger than 2 years old and in children and adolescents 2 to 20 years old as detected with MR imaging. Knowledge of the size of the normal pineal gland is important in the detection of abnormalities of the pineal gland, particularly neoplasms.
Authors: Sameer Farouk Sait; Sofia Haque; Sasan Karimi; Karim J Rebeiz; Jasmine H Francis; Brian P Marr; David H Abramson; Mark M Souweidane; Ira J Dunkel Journal: J Pediatr Hematol Oncol Date: 2020-04 Impact factor: 1.289
Authors: Raya Saab; Carlos Rodriguez-Galindo; Kelly Matmati; Jerold E Rehg; Shannon H Baumer; Joseph D Khoury; Catherine Billups; Geoffrey Neale; Kathleen J Helton; Stephen X Skapek Journal: Cancer Res Date: 2009-01-15 Impact factor: 12.701
Authors: Lara G Sigurdardottir; Sarah C Markt; Sigurdur Sigurdsson; Thor Aspelund; Katja Fall; Eva Schernhammer; Jennifer R Rider; Lenore Launer; Tamara Harris; Meir J Stampfer; Vilmundur Gudnason; Charles A Czeisler; Steven W Lockley; Unnur A Valdimarsdottir; Lorelei A Mucci Journal: J Biol Rhythms Date: 2016-07-22 Impact factor: 3.182