Literature DB >> 8932371

A method for linking yeast artificial chromosomes.

Z Larin1, S S Taylor, C Tyler-Smith.   

Abstract

A method for linking any standard yeast artificial chromosomes (YAC) is described. YACs are introduced into the same cell and joined by mitotic recombination between the vector arms and the homologous sequence in a linking vector; several YACs can be recombined sequentially. The linking vectors also contain the beta-galactosidase gene as an expression reporter in mammalian cells.

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Year:  1996        PMID: 8932371      PMCID: PMC146230          DOI: 10.1093/nar/24.21.4192

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  17 in total

1.  Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping.

Authors:  E D Green; M V Olson
Journal:  Science       Date:  1990-10-05       Impact factor: 47.728

2.  Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors.

Authors:  D T Burke; G F Carle; M V Olson
Journal:  Science       Date:  1987-05-15       Impact factor: 47.728

3.  A first-generation physical map of the human genome.

Authors:  D Cohen; I Chumakov; J Weissenbach
Journal:  Nature       Date:  1993-12-16       Impact factor: 49.962

4.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

5.  Transformation of yeast spheroplasts without cell fusion.

Authors:  P M Burgers; K J Percival
Journal:  Anal Biochem       Date:  1987-06       Impact factor: 3.365

6.  Analysis of extrachromosomal structures containing human centromeric alphoid satellite DNA sequences in mouse cells.

Authors:  S S Taylor; Z Larin; C Tyler-Smith
Journal:  Chromosoma       Date:  1996-08       Impact factor: 4.316

7.  Addition of functional human telomeres to YACs.

Authors:  S S Taylor; Z Larin; C T Smith
Journal:  Hum Mol Genet       Date:  1994-08       Impact factor: 6.150

8.  Yeast kar1 mutants provide an effective method for YAC transfer to new hosts.

Authors:  F Spencer; Y Hugerat; G Simchen; O Hurko; C Connelly; P Hieter
Journal:  Genomics       Date:  1994-07-01       Impact factor: 5.736

9.  Nonrecombinant meiosis I nondisjunction in Saccharomyces cerevisiae induced by tRNA ochre suppressors.

Authors:  E J Louis; J E Haber
Journal:  Genetics       Date:  1989-09       Impact factor: 4.562

10.  A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

Authors:  R S Sikorski; P Hieter
Journal:  Genetics       Date:  1989-05       Impact factor: 4.562

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  2 in total

Review 1.  Genome engineering.

Authors:  Peter A Carr; George M Church
Journal:  Nat Biotechnol       Date:  2009-12       Impact factor: 54.908

2.  Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

Authors:  K A Henning; E A Novotny; S T Compton; X Y Guan; P P Liu; M A Ashlock
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-19       Impact factor: 11.205

  2 in total

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