Literature DB >> 892809

Pi (antitrypsin) typing methods. A comparison of acid starch-gel electrophoresis and isoelectric focusing.

A M Ward, J D Pickering, M K Fagerhol, J P Martin.   

Abstract

The Pi typing methods acid starch-gel electrophoresis (ASGE) and isoelectric focusing (IEF) have been compared by three reference laboratories: 564 samples of phenotypes Pi M, MS and MZ were tested in each of the three laboratories with a 96% agreement on initial typing. The discrepancies are recorded and reasons for disagreement discussed. IEF is a reliable method for Pi typing and gives results comparable to those obtained by ASGE.

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Year:  1977        PMID: 892809     DOI: 10.1159/000152881

Source DB:  PubMed          Journal:  Hum Hered        ISSN: 0001-5652            Impact factor:   0.444


  4 in total

1.  Pi M4: an additional Pi M subtype.

Authors:  J Constans; M Viau; C Gouaillard
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

2.  Alpha-1-antitrypsin Pi S phenotype and liver cell inclusion bodies in alcoholic hepatitis.

Authors:  J K Kelly; T V Taylor; A Milford-Ward
Journal:  J Clin Pathol       Date:  1979-07       Impact factor: 3.411

3.  Segregation distortion of the alpha 1-antitrypsin Pi Z allele.

Authors:  R M Iammarino; D K Wagener; R C Allen
Journal:  Am J Hum Genet       Date:  1979-07       Impact factor: 11.025

4.  Distribution of alpha 1-antitrypsin (PI) phenotypes in chromosome abnormalities.

Authors:  J C Mulley; G R Sutherland
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

  4 in total

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